Evaluation of Palpable Breast Masses With Tc-99M-Mibi - a Comparative-Study With Mammography and Ultrasonography

dc.contributor.authorBurak, Z
dc.contributor.authorArgon, M
dc.contributor.authorMemis, A
dc.contributor.authorErdem, S
dc.contributor.authorBalkan, Z
dc.contributor.authorDuman, Y
dc.contributor.authorUstun, Ee
dc.contributor.authorErhan, Y
dc.contributor.authorOzkilic, H
dc.date.accessioned2019-10-27T11:35:24Z
dc.date.available2019-10-27T11:35:24Z
dc.date.issued1994
dc.departmentEge Üniversitesien_US
dc.description.abstractWe evaluated the feasibility of Tc-99m-methoxyisobutylisonitrile (MIBI) as a tumour localizing agent in patients with palpable breast masses in comparison with mammography and ultrasonography (US). Forty-one patients with palpable masses were studied. An additional 12 women with no palpable breast anomaly also underwent Tc-99m-MIBI breast study. Multiple views were obtained and semiquantitative evaluation was applied. Mammography and US revealed all of the malignant breast masses but differential diagnosis of fibroadenomas could not be achieved. Twenty-five of 27 breast carcinomas were detected using Tc-99m-MIBI scintigraphy. Two patients with invasive lobular carcinoma showed absent MIBI accumulation. Eight of 14 axillary lymph-node metastases showed positive uptake (57%). Twelve of 14 patients with pathologically proven benign breast lesions did not demonstrate any MIBI accumulation. Focal MIBI uptake could be observed in two fibroadenomas. The sensitivity and the specificity of semiquantitative MIBI analysis were 93 and 86%, respectively. Subjective grading offered no additional help in the further differentiation of malignant breast masses. There was no significant difference between histopathological types of breast carcinomas and uptake grades. Our results indicate that Tc-99m-MIBI scintigraphy may provide additional information in the differentiation of malignant pathologies from benign lesions in patients with palpable breast anomalies.en_US
dc.identifier.doi10.1097/00006231-199408000-00005en_US
dc.identifier.endpage612en_US
dc.identifier.issn0143-3636
dc.identifier.issue8en_US
dc.identifier.pmid7970442en_US
dc.identifier.startpage604en_US
dc.identifier.urihttps://doi.org/10.1097/00006231-199408000-00005
dc.identifier.urihttps://hdl.handle.net/11454/33703
dc.identifier.volume15en_US
dc.identifier.wosWOS:A1994PA87900005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherChapman Hall Ltden_US
dc.relation.ispartofNuclear Medicine Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEvaluation of Palpable Breast Masses With Tc-99M-Mibi - a Comparative-Study With Mammography and Ultrasonographyen_US
dc.typeArticleen_US

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