Angiolymphoid hyperplasia with eosinophilia successfully treated with imiquimod: A case report

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disorder characterized by vascular proliferation, eosinophilia in peripheral blood samples and lymphocytosis. The etiology is unknown; this rare condition is generally seen in women. It often presents as multiple, grouped red nodules in the periauricular region, scalp line and neck. Numerous therapeutic approaches have been tried for ALHE including destructive techniques such as electrodesiccation, cryotherapy, surgical excision, radiotherapy or laser (argon, CO2, pulse dye). We present an ALHE case that was treated successfully by using topical imiquimod cream. Copyright © 2007 S. Karger AG.