The value of ultrasonography in detecting early arthropathic changes and contribution to the clinical approach in patients of hemophilia

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dc.authoridSahin, Fahri/0000-0001-9315-8891
dc.authoridtamsel, ipek/0000-0003-3629-2386
dc.authorscopusid6505696955
dc.authorscopusid35885183600
dc.authorscopusid7005245659
dc.authorscopusid57192875053
dc.authorscopusid56021764600
dc.authorscopusid7004923881
dc.authorscopusid6507670897
dc.contributor.authorTamsel, Ipek
dc.contributor.authorKavakli, Kaan
dc.contributor.authorOzbek, S. Sureyya
dc.contributor.authorHekimsoy, Ilhan
dc.contributor.authorBalkan, Can
dc.contributor.authorSahin, Fahri
dc.contributor.authorTamsel, Sadik
dc.date.accessioned2023-01-12T19:49:50Z
dc.date.available2023-01-12T19:49:50Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractPURPOSE\AIM Hemophilia affects the blood clotting process, is a genetic disease characterized by recurrent bleeding. The hemophilia early arthropathy detection with ultrasound (HEAD-US) procedure and scoring method were designed for the detection of early changes in affected joints of patients. In this article, it was aimed to detect early arthropathic changes in the joints of hemophilia patients with the HEAD US scoring system and to investigate its clinical contribution. It was aimed to investigate the effectiveness of HEAD-US scoring in showing early joint damage in subclinical hemophilia cases and its contribution to treatment. METHODS The present study included 50 hemophilia patients who were admitted to Departments of Pediatric and Adult Hematology for routine follow-up. During routine follow-up controls, patients were scored by physical examination and HJHS 2.1 and by ultrasonography and HEAD US. Statistical tests were used to analyze joint health status and the results of US examination in the patient group. RESULTS A total of 294 joints (elbow n = 100, knee n = 94, ankle n = 100) were evaluated by ultrasonography. The mean HJHS and HEAD-US scores of the patients were 14.94 +/- 15.18 and 15.6 +/- 12.6, respectively. CONCLUSIONS HEAD-US is accepted to be more sensitive than HJHS in detecting early signs of arthropathy. Detection of early abnormalities by ultrasonography will enable the development of individualized treatment protocols and to the prevention of arthropathy development.en_US
dc.identifier.doi10.1002/jcu.23164
dc.identifier.endpage432en_US
dc.identifier.issn0091-2751
dc.identifier.issn1097-0096
dc.identifier.issue3en_US
dc.identifier.pmid35235206en_US
dc.identifier.scopus2-s2.0-85125486433en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage428en_US
dc.identifier.urihttps://doi.org/10.1002/jcu.23164
dc.identifier.urihttps://hdl.handle.net/11454/75927
dc.identifier.volume50en_US
dc.identifier.wosWOS:000762964900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Ultrasounden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHEAD-USen_US
dc.subjecthemophiliaen_US
dc.subjectultrasounden_US
dc.subjectHead-Us Systemen_US
dc.subjectDiagnostic-Accuracyen_US
dc.subjectUltrasounden_US
dc.subjectProphylaxisen_US
dc.subjectChildrenen_US
dc.subjectCareen_US
dc.subjectJointsen_US
dc.titleThe value of ultrasonography in detecting early arthropathic changes and contribution to the clinical approach in patients of hemophiliaen_US
dc.typeArticleen_US

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