Respiratory impairment due to asbestos exposure in brake-lining workers

Küçük Resim Yok

Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Academic Press Inc Elsevier Science

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

There is extensive evidence that exposure to asbestos causes pulmonary parenchymal fibrosis, pleural disease, and malignant neoplasm in asbestos-exposed workers. However, few data concerning brake-lining workers are available in the literature. In this study, we aimed to assess the long-term effects of chrysotile asbestos exposure on lung function and the risk of asbestos-related diseases in brake-lining workers. Seventy-four asbestos-exposed workers who processed brake-lining products and 12 unexposed office workers were offered pulmonary function tests (spirometry and transfer factor) in 1992 and 1999. In 1999, the mean duration of asbestos exposure was 10.00+/-4.07 and 11.02+/-4.81 years (7-31 years) in nonsmoking and smoking asbestos workers, respectively. Transfer factor (T-L, CO) and transfer coefficient (K-CO) decline were significant in the 7-year follow-up in both smoking and nonsmoking asbestos workers. However, lung function indices of the control group, whom were all current smokers; were also found to be decreased, including FEF75, T-L, CO and K-CO. We found minimal reticular changes in 10 asbestos workers who were all current smokers, they underwent high-resolution computed tomography scans of the chest and we found that they had peribronchial thickening resulting from smoking. As a conclusion, even in the absence of radiographic asbestosis, T-L, CO and K-CO may decrease after a mean 10-year duration of exposure to asbestos in brake-lining workers and this is more noticeable with cigarette burden. (C) 2003 Elsevier Science (USA). All rights reserved.

Açıklama

Anahtar Kelimeler

brake lining, asbestosis, transfer factor, transfer coefficient, spirometry

Kaynak

Environmental Research

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

91

Sayı

3

Künye