Comparison of heated humidified high-flow nasal cannula flow rates (1-L center dot kg center dot min(-1) vs 2-L center dot kg center dot min (-1)) in the management of acute bronchiolitis

Basit Öğe Kaydı
dc.contributor.authorYurtseven, Ali
dc.contributor.authorTuran, Caner
dc.contributor.authorErseven, Eren
dc.contributor.authorSaz, Eylem Ulas
dc.date.accessioned2019-10-27T09:43:47Z
dc.date.available2019-10-27T09:43:47Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectiveWe aimed to compare the heated humidified high-FLow nasal cannula (HHHFNC) flow rate of 1-Lkgmin(-1) (1L) with 2-Lkgmin (-1) (2L) in patients with severe bronchiolitis presenting to the pediatric emergency department. Study designWe performed a study in which all patients were allocated to receive these two flow rates. The primary outcome was admitted as treatment failure, which was defined as a clinical escalation in respiratory status. Secondary outcomes covered a decrease of respiratory rate (RR), heart rate (HR), the clinical respiratory score (CRS), rise of peripheral capillary oxygen saturation (SpO(2)), and rates of weaning, intubation, and intensive care unit (ICU) admission. ResultsOne hundred and sixty-eight cases (88 received the 1-L flow rate and 80, the 2-L flow rate) were included in the analyses. Treatment failure was 11.4% (10 of 88) in the 1-L group, and 10% (8 of 80) in the 2-L group (P=.775). Significant variation in the intubation rate or the ICU admission rate was not determined. At the 2nd hour, the rate of weaning (53.4% vs 35%; P=.017), the falling down of the CRS (-2.1 vs -1.5; P<.001), RR (-15.2 vs -11.8; P<.001), and HR (-24.8 vs -21.2; P<.001), and the increase of SpO (2) (4.8 vs 3.6; P<.001) were significantly more evident in the 1-L group. ConclusionHHHFNC with the 1-Lkgmin(-1) flow rate, which provides a more frequent earlier effect, reached therapy success as high as the 2-Lkgmin (-1) flow rate in patients with severe acute bronchiolitis.en_US
dc.description.sponsorshipScientific Research Projects of Ege UniversityEge University [2.100.2017.0025]en_US
dc.description.sponsorshipThe Scientific Research Projects of Ege University, Grant/Award Number: 2.100.2017.0025en_US
dc.identifier.doi10.1002/ppul.24318en_US
dc.identifier.endpage900en_US
dc.identifier.issn8755-6863
dc.identifier.issn1099-0496
dc.identifier.issue6en_US
dc.identifier.pmid30887731en_US
dc.identifier.startpage894en_US
dc.identifier.urihttps://doi.org/10.1002/ppul.24318
dc.identifier.urihttps://hdl.handle.net/11454/28911
dc.identifier.volume54en_US
dc.identifier.wosWOS:000474786700036en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatric Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbronchiolitisen_US
dc.subjectemergency deparmenten_US
dc.subjectflow rateen_US
dc.subjecthigh flow nasal cannulaen_US
dc.titleComparison of heated humidified high-flow nasal cannula flow rates (1-L center dot kg center dot min(-1) vs 2-L center dot kg center dot min (-1)) in the management of acute bronchiolitisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu