Measles seroprevalence in Izmir with special emphasis on measles vaccination policy for Turkey

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dc.contributor.authorEgemen A.
dc.contributor.authorAksit S.
dc.contributor.authorOzacar T.
dc.contributor.authorKurugol Z.
dc.contributor.authorKeskinoglu P.
dc.contributor.authorPehlivan T.
dc.contributor.authorMutlu S.
dc.date.accessioned2019-10-27T09:00:06Z
dc.date.available2019-10-27T09:00:06Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Measles outbreaks seem to occur every 2- to 3-year intervals in Turkey. However, seroepidemiological studies are limited, Knowing the prevalence of measles susceptibility as measured either by serologic markers of immunity or surveys of vaccination coverage is an important tool to assess the risk for measles outbreaks. Methods: In order to determine the seroprevalence of measles antibodies among a 1 to 29-year-old population in Izmir (Turkey) and to develop the best vaccination policy for measles, a total of 600 people aged from 1 to 29 were selected for the study with cluster sampling. The information on sociodemographic characteristics, vaccination status and measles history was gathered for each participant. Measles-specific IgG antibodies were screened qualitatively by using microenzyme immune assay for 595 subjects. Results: Of the 595 participants screened for the measles antibodies, 56 (9.4%) were seronegative. The proportion of the susceptible individuals in the age groups of 1-4, 5-9, 10-14, 15-19 and 20-29 was 20.0, 10.4, 6.0, 10.3 and 3.0%, respectively. The logistic regression analysis showed that none of the independent characteristics (sex, socioeconomic status, past measles history, vaccination status) with the exception of age group, was significantly associated with measles seronegativity. Conclusion: The optimal measles vaccination policy for Turkey may be to increase vaccination coverage above 90%, to conduct a catch-up campaign covering persons aged 1-19, regardless of previous vaccination status. Another factor to consider is to adopt a routine two-dose vaccination, giving the first dose at 12- 15 months of age and the second dose at school entry.en_US
dc.identifier.doi10.1046/j.1442-200X.2001.01413.xen_US
dc.identifier.endpage384en_US
dc.identifier.issn1328-8067
dc.identifier.issue4en_US
dc.identifier.pmid11472583en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage379en_US
dc.identifier.urihttps://doi.org/10.1046/j.1442-200X.2001.01413.x
dc.identifier.urihttps://hdl.handle.net/11454/27986
dc.identifier.volume43en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMeaslesen_US
dc.subjectSeroprevalenceen_US
dc.subjectTurkeyen_US
dc.subjectVaccinationen_US
dc.titleMeasles seroprevalence in Izmir with special emphasis on measles vaccination policy for Turkeyen_US
dc.typeArticleen_US

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