The Effect of Lactate and Lactate Clearance on Mortality in Patients with Acute Pulmonary Embolism in Emergency Department

Basit Öğe Kaydı
dc.contributor.authorÖzçete, Enver
dc.contributor.authorUz, İlhan
dc.contributor.authorKaran, Damla
dc.contributor.authorKarbek, Funda
dc.contributor.authorAltuntaş, Simge
dc.date.accessioned2024-08-25T18:53:32Z
dc.date.available2024-08-25T18:53:32Z
dc.date.issued2022
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Pulmonary embolism (PE) is the third leading cause of death due to cardiovascular disease. The presence of shock or hypotension remains the main prognostic clinical marker and to date, it is the only factor that indicates the need for aggressive treatment. Most patients with pulmonary embolism are normotensive. Prognostic indicators are needed to better classify patients with pulmonary embolism. This study aimed to investigate the effect of lactate level on predicting hospital mortality in patients diagnosed with pulmonary embolism in the emergency department, and the effect of lactate clearance on mortality in patients with high lactate levels (lactate ?2 mmol/L). Material and Methods: This study was designed as a retrospective study. Adult patients (>18-years old) who were diagnosed with PE by computed tomography angiography of the thorax in the university hospital emergency between January 1, 2018, and December 31, 2019, were analyzed. Results: A total of 367 patients were diagnosed with pulmonary embolism in the emergency department. In-hospital mortality rate of the patients was 29.8% and the pulmonary embolism-related mortality rate was 12.4%. Lactate clearance was not significant in predicting mortality risk. In the logistic regression analysis performed among the risk factors affecting mortality in patients with pulmonary embolism, lactate ?3 mmol/L and normotensive + lactate ?3 mmol/L were significant in predicting in-hospital mortality. Conclusion: The lactate level in the emergency department could be an effective screening method for identifying mortality in acute pulmonary embolism patients.en_US
dc.identifier.doi10.54996/anatolianjem.1022243
dc.identifier.endpage73en_US
dc.identifier.issn2651-4311
dc.identifier.issue2en_US
dc.identifier.startpage68en_US
dc.identifier.trdizinid1113486en_US
dc.identifier.urihttps://doi.org/10.54996/anatolianjem.1022243
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1113486
dc.identifier.urihttps://hdl.handle.net/11454/103140
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnatolian Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectMortalityen_US
dc.subjectpulmonary embolismen_US
dc.subjectemergency medicineen_US
dc.titleThe Effect of Lactate and Lactate Clearance on Mortality in Patients with Acute Pulmonary Embolism in Emergency Departmenten_US
dc.typeArticleen_US

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