Is it possible to predict sepsis, the most serious complication in prostate biopsy?

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dc.contributor.authorSimsir A.
dc.contributor.authorKismali E.
dc.contributor.authorMammadov R.
dc.contributor.authorGunaydin G.
dc.contributor.authorCal C.
dc.date.accessioned2019-10-27T08:35:03Z
dc.date.available2019-10-27T08:35:03Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Prostate biopsy for the diagnosis of prostate cancer by transrectal ultrasonography (TRUS) is a common procedure used in daily urology practice with a low complication rate and easy applicability. In this study, the precipitating factors and prophylaxis for sepsis, the worst complication of the procedure, were assessed. Patients and Methods: 2,023 patients with suspected prostate cancer who underwent biopsy by TRUS in one center were assessed retrospectively. The relationship between sepsis and age, serum total prostate-specific antigen (PSA) level, PSA density, prostate volume, number of biopsies, number of repeated biopsies, accompanying diagnosis of prostatitis, presence of urethral catheter, and presence of diabetes mellitus was assessed. Data were analyzed using the t test and logistic regression analysis. Results: Of the 2,023 patients, 62 (3.06%) developed sepsis within 5 days after biopsy. There was no significant relationship between the biopsy and the above parameters using the logistic regression analysis. Using the t test, it was found that the number of biopsy cores (p < 0.001), presence of urethral catheter (p < 0.0001), and presence of diabetes mellitus (p < 0.0001) were predictive factors for sepsis. Conclusion: Sepsis is a rare but life-threatening complication after prostate biopsy by TRUS. Although preoperative prophylactic oral antibiotics and enema before biopsy have proven to be effective in decreasing urinary tract infection rates, patients with urethral catheter, diabetes mellitus or those to undergo biopsy from more sites than ten cores should be closely monitored after biopsy. © 2010 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000296290en_US
dc.identifier.endpage399en_US
dc.identifier.issn0042-1138
dc.identifier.issue4en_US
dc.identifier.pmid20224265en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage395en_US
dc.identifier.urihttps://doi.org/10.1159/000296290
dc.identifier.urihttps://hdl.handle.net/11454/27163
dc.identifier.volume84en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherS. Karger AGen_US
dc.relation.ispartofUrologia Internationalisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProstate biopsyen_US
dc.subjectProstate biopsy sepsisen_US
dc.subjectProstate canceren_US
dc.subjectTransrectal ultrasonographyen_US
dc.titleIs it possible to predict sepsis, the most serious complication in prostate biopsy?en_US
dc.typeArticleen_US

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