Does Concentrated Growth Factor Used With Allografts in Maxillary Sinus Lifting Have Adjunctive Benefits?

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dc.contributor.authorAdalı, E.
dc.contributor.authorYüce, M.O.
dc.contributor.authorGünbay, T.
dc.contributor.authorGünbay, S.
dc.date.accessioned2020-12-01T11:52:57Z
dc.date.available2020-12-01T11:52:57Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: Recent studies have shown that the use of platelet concentration products alone, or in combination with variable graft materials, accelerates the new bone formation associated with sinus augmentation. The aim of this study was to measure the adjunctive effects of concentrated growth factor (CGF) used with allograft on new bone formation and augmentation stability in sinus lifting. Materials and Methods: This randomized controlled study included patients who presented for dental implant placement in atrophic posterior maxilla at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ege University, and who needed maxillary sinus augmentation. All patients were treated with a 2-stage surgical technique using sinus lifting bilaterally and implant placement 6 months later. During sinus lifting surgery, one side was grafted with allograft (group 1) and the other side with allograft mixed CGF (group 2). Cone-beam computed tomography was carried out immediately postoperatively and also 6 months after the augmentation to evaluate vertical bone height and percentage of resorption. Bone specimens were obtained at the time of implant placement and evaluated histomorphometrically to analyze the percentage of new bone formation and residual graft particle. Statistical comparisons were conducted between groups for all these measurements. Results: A total of 10 patients (2 females and 8 males) with a mean age of 57 years (range, 39 to 72) were enrolled in the study. Cone-beam computed tomography analysis revealed a significantly higher percentage of bone height resorption at the sixth month in group 1 (median, 9.32%) compared with group 2 (median, 6.37%) (P <.05). According to the histomorphometric examination, the percentage of new bone formation in group 2 (median, 36.41%) was higher than group 1 (median, 35.49%), but this difference did not reach statistical significance. Conclusions: Using CGF with allografts supports the stabilization of gained vertical bone height after sinus augmentation, but further research is needed to determine the accelerating effects of CGF on new bone formation. © 2020 American Association of Oral and Maxillofacial Surgeonsen_US
dc.description.sponsorshipConflict of Interest Disclosures: None of the authors have any relevant financial relationship(s) with a commercial interest.en_US
dc.identifier.doi10.1016/j.joms.2020.07.217en_US
dc.identifier.issn0278-2391
dc.identifier.pmid32866488en_US
dc.identifier.scopus2-s2.0-85090479807en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1016/j.joms.2020.07.217
dc.identifier.urihttps://hdl.handle.net/11454/61698
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW.B. Saundersen_US
dc.relation.ispartofJournal of Oral and Maxillofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDoes Concentrated Growth Factor Used With Allografts in Maxillary Sinus Lifting Have Adjunctive Benefits?en_US
dc.typeArticleen_US

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