Seroprevalence of hepatitis A, B, and C viruses in Turkish alcoholic cirrhotics and the impact of hepatitis B on clinical profile

Basit Öğe Kaydı
dc.contributor.authorTekin, Fatih
dc.contributor.authorGunsar, Fulya
dc.contributor.authorErdogan, Elvan Isik
dc.contributor.authorSertoz, Ruchan Yazan
dc.contributor.authorKarasu, Zeki
dc.contributor.authorErsoz, Galip
dc.contributor.authorOzutemiz, Omer
dc.contributor.authorAkarca, Ulus
dc.date.accessioned2019-10-27T23:02:05Z
dc.date.available2019-10-27T23:02:05Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: The aims of this study were to detect the seroprevalence of hepatitis A, B, and C viruses in Turkish alcoholic cirrhotics, and to evaluate the impact of hepatitis B infection on clinical profile at first admittance. Methodology: Serological markers for hepatitis A, B, and C viruses in 300 alcoholic cirrhotics diagnosed between January 1994 and December 2012 were retrospectively reviewed. Among them, 148 eligible patients were divided into group 1 (HBsAg positive, n = 43) and group 2 (HBsAg and anti-HBc negative, n = 105). Clinical characteristics at first admittance of groups 1 and 2 were compared. Results: The seroprevalence of anti-HAV total, HBsAg, and anti-HCV was found to be 91.5%, 16.3%, and 8.2%, respectively. The prevalence of hepatocellular carcinoma was higher in the HbsAg-positive group compared to HbsAg-and anti-HBc-negative group (16.3% vs. 2.9%, p = 0.007). Other clinical features were similar in the two groups. Conclusions: Alcoholic cirrhotics have higher frequencies of HBsAg and anti-HCV than the general population. These patients should be investigated for coexistent HBV and HCV infections, and HBV vaccination should not be neglected. Alcoholic cirrhotic patients with concomitant HBV infection should be closely screened for hepatocellular carcinoma.en_US
dc.identifier.doi10.3855/jidc.6002en_US
dc.identifier.endpage258en_US
dc.identifier.issn1972-2680
dc.identifier.issue3en_US
dc.identifier.pmid25771462en_US
dc.identifier.startpage254en_US
dc.identifier.urihttps://doi.org/10.3855/jidc.6002
dc.identifier.urihttps://hdl.handle.net/11454/52249
dc.identifier.volume9en_US
dc.identifier.wosWOS:000352299000005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Infection Developing Countriesen_US
dc.relation.ispartofJournal of Infection in Developing Countriesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectalcoholic cirrhosisen_US
dc.subjectviral hepatitisen_US
dc.subjectseroprevalenceen_US
dc.subjectTurkeyen_US
dc.titleSeroprevalence of hepatitis A, B, and C viruses in Turkish alcoholic cirrhotics and the impact of hepatitis B on clinical profileen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu