Mammographic features of local recurrence after conservative surgery and radiation therapy: Comparison with that of the primary tumor

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dc.contributor.authorGuenhan-Bilgen, I.
dc.contributor.authorOktay, A.
dc.date.accessioned2019-10-27T19:36:56Z
dc.date.available2019-10-27T19:36:56Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To compare the mammographic features of recurrent breast cancer with those of the primary tumor and to determine whether certain mammographic features are associated with a higher risk of local recurrence after breast-conserving therapy. Material and Methods: A retrospective review of mammograms of 421 patients who were treated with conservative surgery and radiotherapy revealed 41 recurrent tumors. Mammographic findings, location, and histopathologic characteristics were retrospectively compared between primary and recurrent tumors. Results: Recurrent tumors were similar in mammographic appearance to primary tumors in 27 (66%) cases. Of 27 primary tumors that occurred as masses without calcifications, 19 (70%) recurred as a mass, and of the six isolated calcifications, five (83%) recurred with calcifications. Ten (53%) of the 19 recurrent masses and five (100%) of the five recurrent calcifications had morphologic features that were similar to those of the primary tumor. Ninety-two percent (11/12) of the recurrences containing microcalcifications ( isolated or associated with a mass) had microcalcifications in their primary tumor. Of 27 masses that recurred, the morphology of the primary tumor was obscured in 13 (48%), ill defined in 10 (37%), and spiculated in four (15%) of the masses. Seventy-six percent (31/41) of recurrences were within the lumpectomy quadrant. In 25 (61%) cases, the histologic findings from the primary tumor and the recurrence were identical. Conclusion: The majority of recurrent tumors appear to be mammographically similar to primary tumors. Therefore, it is important to review preoperative mammograms during follow-up of these patients. Although the study population is small, it was noted that mass with spiculated contour is associated with a lower risk for local recurrence.en_US
dc.identifier.doi10.1080/02841850701199900en_US
dc.identifier.endpage397en_US
dc.identifier.issn0284-1851
dc.identifier.issn1600-0455
dc.identifier.issue4en_US
dc.identifier.pmid17453518en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage390en_US
dc.identifier.urihttps://doi.org/10.1080/02841850701199900
dc.identifier.urihttps://hdl.handle.net/11454/39915
dc.identifier.volume48en_US
dc.identifier.wosWOS:000246782700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofActa Radiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbreast canceren_US
dc.subjectbreast-conserving therapyen_US
dc.subjectlocal recurrenceen_US
dc.subjectmammographyen_US
dc.titleMammographic features of local recurrence after conservative surgery and radiation therapy: Comparison with that of the primary tumoren_US
dc.typeArticleen_US

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