The significance of immunonutrition nutritional support in patients undergoing postoperative adjuvant chemotherapy for lung cancer: case-control study

dc.authoridCAGIRICI, UFUK/0000-0001-7827-793X
dc.authorscopusid55343779100
dc.authorscopusid57212532836
dc.authorscopusid57194346598
dc.authorscopusid37052683100
dc.authorscopusid55343710200
dc.authorscopusid8429335700
dc.authorscopusid6602854011
dc.authorwosidCAGIRICI, UFUK/X-1303-2018
dc.contributor.authorAkcam, Tevfik Ilker
dc.contributor.authorTekneci, Ahmet Kayahan
dc.contributor.authorKavurmaci, Onder
dc.contributor.authorOzdil, Ali
dc.contributor.authorErgonul, Ayse Gul
dc.contributor.authorTurhan, Kutsal
dc.contributor.authorCakan, Alpaslan
dc.date.accessioned2024-08-25T18:53:34Z
dc.date.available2024-08-25T18:53:34Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractBackgroundIn this study, the effect of postoperative early nutritional supplementation on the course of the disease was investigated in patients who were operated for non-small cell lung cancer and received adjuvant chemotherapy.MethodsThe study examined the data of patients who anatomical pulmonary resection for non-small cell lung cancer and who were treated with adjuvant chemotherapy at our clinic between January 2014 and January 2020. Patients who received early postoperative nutritional supplements and those who continued with a normal diet were compared in terms of complications, mortality, recurrence, and survival.ResultsThe study sample consisted of 68 (84%) male and 13 (16%) female patients, and the mean duration of postoperative follow-up was 31.6 +/- 17.9 (4-75) months. Metastasis was identified in eight (17.4%) patients in Grup(NS (Nutritional Supplements)) compared to 10 (28.6%) patients in Group(C (Control)) (p = 0.231). Of the total, 11 (23.9%) patients died in Group(NS) compared to 13 (37.1%) in Group(C) (p = 0.196). Mean survival was 58.9 +/- 3.8 (95% CI: 4.0-75.0) months in Group(NS) compared to 43.5 +/- 4.6 (95% CI: 6.0-66.0) months in Group(C) (p = 0.045).ConclusionEarly nutritional supplements should be considered as having a positive effect especially on survival in this specific patient group involving factors with high catabolic effects, such as neoplasia, operation, and chemotherapy together.en_US
dc.identifier.doi10.1186/s12957-023-03073-y
dc.identifier.issn1477-7819
dc.identifier.issue1en_US
dc.identifier.pmid37337249en_US
dc.identifier.scopus2-s2.0-85162228931en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s12957-023-03073-y
dc.identifier.urihttps://hdl.handle.net/11454/103157
dc.identifier.volume21en_US
dc.identifier.wosWOS:001010838900003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBMCen_US
dc.relation.ispartofWorld Journal of Surgical Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectLung canceren_US
dc.subjectNutritionen_US
dc.subjectResectionen_US
dc.subjectAdjuvant chemotherapyen_US
dc.subjectOpen-Labelen_US
dc.subjectMalnutritionen_US
dc.subjectMulticenteren_US
dc.subjectCriteriaen_US
dc.titleThe significance of immunonutrition nutritional support in patients undergoing postoperative adjuvant chemotherapy for lung cancer: case-control studyen_US
dc.typeArticleen_US

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