Evaluation of Ex-PRESS Mini Glaucoma Shunt Implantation in Refractory Postpenetrating Keratoplasty Glaucoma

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dc.contributor.authorAtes, Halil
dc.contributor.authorPalamar, Melis
dc.contributor.authorYagci, Ayse
dc.contributor.authorEgrilmez, Sait
dc.date.accessioned2019-10-27T21:14:41Z
dc.date.available2019-10-27T21:14:41Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To evaluate the intraocular pressure (IOP) control and graft survival after Ex-PRESS mini glaucoma shunt implantation in refractory postpenetrating keratoplasty glaucoma. Methods: The study included postpenetrating keratoplasty glaucoma cases unresponsive to medical antiglaucomatous therapy in whom 15 Ex-PRESS mini glaucoma shunt implantation was carried out. All glaucoma shunt implantations were performed in a separate session after penetrating keratoplasty. Nine operations were performed under general anesthesia and 6 were performed under local anesthesia. Topical antibiotherapy and topical corticosteroids were used during the postoperative first month. Results: Mean age of the study population was 37.4 years (range: 10 to 80 y). IOP decreased from 41.46 mm Hg (range: 26 to 80 mm Hg) to 12.06 mm Hg (range: 8 to 25 mm Hg) over a mean follow-up of 12.2 months (range: 8 to 19 mo) (P<0.001; Wilcoxon signed rank test). IOP was below 21 mm Hg in 14 of 15 eyes (93.3%) with or without antiglaucomatous drugs. Complete success (IOP < 21 mm Hg without medication) rate was 86.6%. Average number of antiglaucomatous drug usage decreased from 3.20 (range: 2 to 4) preoperatively to 0.26 postoperatively (range: 0 to 3) (P < 0.001; Wilcoxon signed rank test). In 93.3% of the cases, the decrease in IOP was 30% or above postoperatively. After Ex-PRESS implantation, clear grafts remained clear while edematous grafts became clearer due to IOP decrease. Neither biomicroscopy nor pachymetry showed worsening of preoperatively opaque grafts. Conclusion: Ex-PRESS mini glaucoma shunt implantation may be an effective procedure for refractory postpenetrating keratoplasty glaucoma with acceptable graft failure rates in short term.en_US
dc.identifier.doi10.1097/IJG.0b013e3181ca76d9en_US
dc.identifier.endpage560en_US
dc.identifier.issn1057-0829
dc.identifier.issn1536-481X
dc.identifier.issue8en_US
dc.identifier.pmid20164799en_US
dc.identifier.startpage556en_US
dc.identifier.urihttps://doi.org/10.1097/IJG.0b013e3181ca76d9
dc.identifier.urihttps://hdl.handle.net/11454/43423
dc.identifier.volume19en_US
dc.identifier.wosWOS:000282986300011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal of Glaucomaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpenetrating keratoplastyen_US
dc.subjectglaucomaen_US
dc.subjectglaucoma drainage deviceen_US
dc.subjectEx-PRESSen_US
dc.titleEvaluation of Ex-PRESS Mini Glaucoma Shunt Implantation in Refractory Postpenetrating Keratoplasty Glaucomaen_US
dc.typeArticleen_US

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