Exploring the intricate relationship between miRNA dysregulation and breast cancer development: insights into the impact of environmental chemicals

Basit Öğe Kaydı
dc.contributor.authorAbolhasanzadeh, Narges
dc.contributor.authorSarabandi, Sajed
dc.contributor.authorDehghan, Bahar
dc.contributor.authorKaramad, Vahidreza
dc.contributor.authorAvci, Cigir Biray
dc.contributor.authorShademan, Behrouz
dc.contributor.authorNourazarian, Alireza
dc.date.accessioned2024-08-31T07:47:29Z
dc.date.available2024-08-31T07:47:29Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractBreast cancer stands as the most prevalent form of cancer among women globally, influenced by a combination of genetic and environmental factors. Recent studies have investigated changes in microRNAs (miRNAs) during breast cancer progression and the potential impact of environmental chemicals on miRNA expression. This review aims to provide an updated overview of miRNA alterations in breast cancer and to explore their potential association with environmental chemicals. We will discuss the current knowledge on dysregulated miRNAs in breast cancer, including both upregulated and downregulated miRNAs. Additionally, we will review the influence of environmental chemicals, such as endocrine-disrupting compounds, heavy metals, and air pollutants, on miRNA expression and their potential contribution to breast cancer development. This review aims to advance our understanding of the complex molecular mechanisms underlying miRNA dysregulation in breast cancer by comprehensively examining miRNA alterations and their association with environmental chemicals. This knowledge is crucial for the development of targeted therapies and preventive measures. Furthermore, identifying specific miRNAs affected by environmental chemicals may allow the prediction of individual susceptibility to breast cancer and the design of personalized intervention strategies.en_US
dc.identifier.doi10.3389/fimmu.2024.1333563
dc.identifier.issn1664-3224
dc.identifier.pmid38807590en_US
dc.identifier.scopus2-s2.0-85194396080en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3389/fimmu.2024.1333563
dc.identifier.urihttps://hdl.handle.net/11454/104438
dc.identifier.volume15en_US
dc.identifier.wosWOS:001231919600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFrontiers Media Saen_US
dc.relation.ispartofFrontiers In Immunologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectBreast Canceren_US
dc.subjectMicrornasen_US
dc.subjectEnvironmental Chemicalsen_US
dc.subjectHeavy Metalsen_US
dc.subjectAir Pollutantsen_US
dc.titleExploring the intricate relationship between miRNA dysregulation and breast cancer development: insights into the impact of environmental chemicalsen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu