Patients with post-polio syndrome are more likely to have subclinical involvement as compared to polio survivors without new symptoms

Basit Öğe Kaydı
dc.contributor.authorOn, Arzu Yagiz
dc.contributor.authorSungur, Ulas
dc.date.accessioned2019-10-27T22:58:22Z
dc.date.available2019-10-27T22:58:22Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Post-polio syndrome (PPS) is a condition that affects polio survivors decades after recovery from an initial acute attack. It is a well-known entity that limbs thought to be nonaffected by polio survivors commonly demonstrate electromyography (EMG) evidence of prior polio. Although the diagnosis of PPS requires a remote history of acute paralytic polio, clinically unapparent damage caused by poliovirus can be associated with PPS later in life. Objective: To evaluate EMG abnormalities and late progressive symptoms in limbs thought to be nonaffected by polio survivors, in order to determine the prevalence of subclinical motor neuron involvement in those fulfilling criteria for PPS comparing to those without such symptoms. Materials and Methods: Clinical and EMG findings of 464 limbs in 116 polio survivors who had been admitted to our clinic were analyzed. Affection of the limbs by polio was classified based on the patient's self-report on remote weakness during the acute phase of poliomyelitis, muscle strength measured by manual muscle testing, and four-limb needle EMG. Results: Seventy-six of the patients (65.5%) met the criteria of PPS. Needle EMG studies revealed subclinical involvement in 122 out of 293 (42%) limbs with no history of remote weakness during the acute phase of poliomyelitis. Prevalence of subclinical involvement was found 47% in polio survivors who met the criteria of PPS compared to 33% in those without PPS (P = 0.013). Among the limbs that had developed new weakness in PPS patients, 33.5% had subclinical involvement. Discussion and Conclusion: Subclinical involvement is common in limbs thought to be nonaffected by polio survivors, and this is especially present in those fulfilling criteria for PPS. New muscle weakness may develop in apparently nonaffected, subclinically involved muscles. Thus we believe that four-limb EMG studies should be performed in all polio survivors, especially in those with the symptoms of PPS.en_US
dc.identifier.doi10.4103/0972-2327.167705en_US
dc.identifier.endpage47en_US
dc.identifier.issn0972-2327
dc.identifier.issn1998-3549
dc.identifier.issue1en_US
dc.identifier.pmid27011627en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage44en_US
dc.identifier.urihttps://doi.org/10.4103/0972-2327.167705
dc.identifier.urihttps://hdl.handle.net/11454/51528
dc.identifier.volume19en_US
dc.identifier.wosWOS:000370332900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofAnnals of Indian Academy of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElectromyographyen_US
dc.subjectpoliomyelitisen_US
dc.subjectpost-polio syndromeen_US
dc.titlePatients with post-polio syndrome are more likely to have subclinical involvement as compared to polio survivors without new symptomsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu