Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure

Basit Öğe Kaydı
dc.contributor.authorDuygu, H.
dc.contributor.authorOzerkan, F.
dc.contributor.authorZoghi, M.
dc.contributor.authorNalbantgil, S.
dc.contributor.authorYildiz, A.
dc.contributor.authorAkilli, A.
dc.contributor.authorAkin, M.
dc.contributor.authorNazli, C.
dc.contributor.authorErgene, O.
dc.date.accessioned2019-10-27T19:55:36Z
dc.date.available2019-10-27T19:55:36Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Levosimendan is a novel positive inotropic calcium sensitiser agent used in acute left heart failure. In this study, the effect of levosimendan on the right ventricular systolic and diastolic functions was evaluated by tissue Doppler comparing them with dobutamine in patients with ischaemic heart failure. Methods: Patients having an acute decompensated heart failure with ischaemic cardiomyopathy and left ventricular ejection fraction < 40% were included in the study. Before and 24-h after treatment, peak systolic (Sa), peak early (Ea), peak late (Aa) diastolic annular velocities and Ea/Aa ratio from tricuspid lateral annulus by tissue Doppler and systolic pulmonary artery pressure (SPAP) were measured. Results: Sa, Ea and the Ea/Aa ratio were significantly increased in the levosimendan group whereas SPAP was significantly reduced. In the dobutamine group, no significant differences were observed in the Sa, Ea, Aa and Ea/Aa ratio in spite of a significant reduction in SPAP. Decrease in SPAP was greater in the levosimendan group (p = 0.002). Conclusion: Levosimendan improves right ventricular systolic and diastolic functions.en_US
dc.identifier.doi10.1111/j.1742-1241.2007.01510.xen_US
dc.identifier.endpage233en_US
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue2en_US
dc.identifier.pmid17949428en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage228en_US
dc.identifier.urihttps://doi.org/10.1111/j.1742-1241.2007.01510.x
dc.identifier.urihttps://hdl.handle.net/11454/40707
dc.identifier.volume62en_US
dc.identifier.wosWOS:000252322200014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEffect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failureen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu