Plasma İnterleukin-7 (Il-7) and Il-8 Concentrations İn Acute Rheumatic Fever and Chronic Rheumatic Heart Disease
Küçük Resim Yok
Tarih
1995
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Scandinavian University Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Interleukin-7 (IL-7) and IL-8 productions in 25 children with acute rheumatic fever (ARF) and in 15 children with chronic rheumatic heart disease (CRHD) and in 15 children with streptococcal pharyngitis (SP), were investigated in order to determine whether they have a role in the pathogenesis of rheumatic fever. Significantly higher IL-8 levels were found in ARF patients in the clinically active period. IL-7 concentrations remained unchanged during different stages of rheumatic fever. The decrease of elevated IL-8 concentrations within 3 months and normal IL-8 concentrations in patients with CRHD and SP indicate an excessive production of IL-8, probably by cellular infiltrates in the joint throughout the active period of rheumatic disease.
Açıklama
Anahtar Kelimeler
acute rheumatic fever, chronic rheumatic heart diseases, streptococcal pharyngitis, interleukin-7, interleukin-8
Kaynak
Scandinavian Journal of Rheumatology
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
24
Sayı
6
