Comparison of the inhibitory response to tendon and cutaneous afferent stimulation in the human lower limb

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dc.contributor.authorRogasch, Nigel C.
dc.contributor.authorBurne, John A.
dc.contributor.authorTurker, Kemal S.
dc.date.accessioned2019-10-27T21:34:41Z
dc.date.available2019-10-27T21:34:41Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractRogasch NC, Burne JA, Turker KS. Comparison of the inhibitory response to tendon and cutaneous afferent stimulation in the human lower limb. J Neurophysiol 107: 564-572, 2012. First published October 26, 2011; doi:10.1152/jn.00751.2011.-A powerful early inhibition is seen in triceps surae after transcutaneous electrical stimulation of the Achilles tendon [tendon electrical stimulation (TES)]. The aim of the present study was to confirm results from surface electromyogram (SEMG) recordings that the inhibition is not wholly or partly due to stimulation of cutaneous afferents that may lie within range of the tendon electrodes. Because of methodological limitations, SEMG does not reliably identify the time course of inhibitory and excitatory reflex components. This issue was revisited here with an analysis of changes in single motor unit (SMU) firing rate [peristimulus frequencygram (PSF)] and probability [peristimulus time histogram (PSTH)] to reexamine the time course of inhibitory SMU events that follow purely cutaneous (superficial sural) nerve stimulation. Results were then compared with similar data from TES. When compared with the reflex response to TES, sural nerve stimulation resulted in a longer onset latency of the primary inhibition and a weaker effect on SMU firing probability and rate. PSF also revealed that decreased SMU firing rates persisted during the excitation phase in SEMG, suggesting that the initial inhibition was more prolonged than previously reported. In a further study, the transcutaneous SEMG Achilles tendon response was compared with that from direct intra-tendon stimulation with insulated needle electrodes. This method should attenuate the SEMG response if it is wholly or partly dependent on cutaneous afferents. However, subcutaneous stimulation of the tendon produced similar components in the SEMG, confirming that cutaneous afferents made little or no contribution to the initial inhibition following TES.en_US
dc.description.sponsorshipNational Health and Medical Research Council of AustraliaNational Health and Medical Research Council of Australia [607223]; Marie Curie Chair projectEuropean Union (EU) [MEX-CT-2006-040317]; Turkish Scientific and Technological Research OrganisationTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [107S029-SBAG-3556]en_US
dc.description.sponsorshipN. C. Rogasch is supported by a postgraduate biomedical research scholarship from the National Health and Medical Research Council of Australia (607223). K. S. Turker holds the Marie Curie Chair of the European Union. This work was supported by the Marie Curie Chair project (GenderReflex; MEX-CT-2006-040317) and the Turkish Scientific and Technological Research Organisation (107S029-SBAG-3556).en_US
dc.identifier.doi10.1152/jn.00751.2011en_US
dc.identifier.endpage572en_US
dc.identifier.issn0022-3077
dc.identifier.issue2en_US
dc.identifier.pmid22031770en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage564en_US
dc.identifier.urihttps://doi.org/10.1152/jn.00751.2011
dc.identifier.urihttps://hdl.handle.net/11454/45662
dc.identifier.volume107en_US
dc.identifier.wosWOS:000299167000005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Physiological Socen_US
dc.relation.ispartofJournal of Neurophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttendon electrical stimulationen_US
dc.subjectsural nerve stimulationen_US
dc.subjectperistimulus time histogramen_US
dc.subjectperistimulus frequencygramen_US
dc.titleComparison of the inhibitory response to tendon and cutaneous afferent stimulation in the human lower limben_US
dc.typeArticleen_US

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