A rare central nervous system tumor of childhood with spongiform appearance on brain magnetic resonance imaging; primary diffuse leptomeningeal oligodendrogliomatosis

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dc.authorscopusid25222311100
dc.authorscopusid55633787300
dc.authorscopusid57201184233
dc.contributor.authorTekin, Hande Gazeteci
dc.contributor.authorKaraoglu, Pakize
dc.contributor.authorBolat, Elif
dc.date.accessioned2023-01-12T19:55:58Z
dc.date.available2023-01-12T19:55:58Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractdiffuse leptomeningeal oligodendrogliomatosis is a rare fatal tumor of childhood. Symptoms usually occur when the tumor causes hydrocephalus. Brain magnetic resonance imaging (MRI) may be nearly normal in the early stages of the disease, while hydrocephalus and multiple leptomeningeal cysts with spongiform appearance may appear later on. One may consider the diagnosis when radiologic findings become apparent with multiple leptomeningeal cysts. However, failure to recognize the imaging findings due to the rarity of the disease may delay the diagnosis. Here, we report a 3.5-year-old girl who presented with ataxia and vomiting and had a diagnosis of primary diffuse leptomeningeal glioneuronal tumor with remarkable brain MRI findings as diffuse multiple tiny cystic lesions on the brain and spinal cord. She benefited from radiotherapy and temozolomide treatment with remission of brain MRI findings. Increasing the number of reported cases will enable the elucidation of the disease's pathogenesis and the development of treatment protocols. (C) 2021 Sociedad Espanola de Neurocirug ' ia. Published by Elsevier Espana, S.L.U. All rights reserved.en_US
dc.identifier.doi10.1016/j.neucir.2020.12.004
dc.identifier.endpage194en_US
dc.identifier.issn1130-1473
dc.identifier.issn2340-6305
dc.identifier.issue4en_US
dc.identifier.pmid33549480en_US
dc.identifier.scopus2-s2.0-85132306318en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage190en_US
dc.identifier.urihttps://doi.org/10.1016/j.neucir.2020.12.004
dc.identifier.urihttps://hdl.handle.net/11454/76779
dc.identifier.volume33en_US
dc.identifier.wosWOS:000862717200005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Espana Sluen_US
dc.relation.ispartofNeurocirugiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCentral nervous system tumoren_US
dc.subjectChildrenen_US
dc.subjectPrimary diffuse leptomeningeal tumoraen_US
dc.subjectGliomatosisen_US
dc.titleA rare central nervous system tumor of childhood with spongiform appearance on brain magnetic resonance imaging; primary diffuse leptomeningeal oligodendrogliomatosisen_US
dc.typeArticleen_US

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