Utility of CHA(2)DS(2)-VASc and HAS-BLED Scores as Predictor of Thromboembolism and Bleeding After Left Ventricular Assist Device Implantation
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Ischemic and hemorrhagic events are the common causes of morbidity and mortality after continuous-flow left ventricular assist device (CF-LVAD) implantation. CHA(2)DS(2)-VASc score predicts thromboembolic (TE) event risk and HAS-BLED score predicts bleeding risk in patients on anticoagulant with atrial fibrillation (AF). We aimed to evaluate whether these scoring systems would be predictive of TE and bleeding complications after CF-LVAD implantation. From December 2010 to December 2014, 145 patients who underwent CF-LVAD implantation at a single center were included. Mean age was 50.7 +/- 11.2 years, and 85.5% were male. Baseline CHA(2)DS(2)-VASc and HAS-BLED scores were retrospectively determined for patients with CF-LVADs. After device implantation, all patients were on warfarin (target international normalized ratio 2-3) as well as 300 mg of aspirin daily. Median length of support was 316 days (range 31-1,060), with 22 TE events (15.2%) and 32 bleeding (22.1%) events. The mean CHA(2)DS(2)-VASc score was 2.3 +/- 1.4 and 2.5 +/- 1.2 (p = 0.2) in patients with and without TE event, respectively. The mean HAS-BLED score was 1.8 +/- 0.8 and 1.42 +/- 0.6 (p = 0.004) in patients with and without bleeding, respectively. Baseline high HAS-BLED score was predictive of bleeding events after CF-LVAD implantation, whereas baseline CHA(2)DS(2)-VASc score was not predictive of TE events.
Açıklama
Anahtar Kelimeler
bleeding, continuous-flow left ventricular assist device, CHA(2)DS(2)-VASc, HAS-BLED, thromboembolism
Kaynak
Asaio Journal
WoS Q Değeri
Q3
Scopus Q Değeri
Cilt
63
Sayı
6
