Different Neurologic Aspects of Nutritional B-12 Deficiency in Infancy

Küçük Resim Yok

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Sage Publications Inc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The objective of this study is to evaluate neurologic problems caused by nutritional vitamin B-12 deficiency in infancy. Twenty-four cases between 2 and 18 months of age with neurologic symptoms and/or signs and diagnosed as nutritional vitamin B-12 deficiency were analyzed. The most common symptoms were developmental retardation, afebrile seizures, and involuntary movements. The mean vitamin B-12 levels were lower in patients with both neurologic and extraneurologic involvement when compared to those with only neurologic symptoms. All of the cases were treated with vitamin B-12. In patients with severe deficiencies, involuntary movements were observed during vitamin B-12 treatment using cyanocobalamin form. At the 1-year follow-up, all but 3 patients were considered neurodevelopmentally normal. The 3 patients that did not fully recover, on admission, had the lowest vitamin B-12 levels. It is of great importance to prevent, diagnose, and treat vitamin B-12 deficiency promptly to prevent the long-term neurologic problems.

Açıklama

Anahtar Kelimeler

B-12 vitamin, infancy, neurologic, development, seizure, involuntary movement

Kaynak

Journal of Child Neurology

WoS Q Değeri

Q3

Scopus Q Değeri

Cilt

31

Sayı

5

Künye