Negative prognostic factors in colorectal carcinoma: An analysis of 448 patients

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dc.contributor.authorCaliskan, Cemil
dc.contributor.authorGuler, Necdet
dc.contributor.authorKaraca, Can
dc.contributor.authorMakay, Ozer
dc.contributor.authorFirat, Ozgur
dc.contributor.authorKorkut, Mustafa A.
dc.date.accessioned2019-10-27T21:17:17Z
dc.date.available2019-10-27T21:17:17Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractColorectal carcinoma (CRC) is the most frequent malignancy of the gastrointestinal tract. Prognostic researches are carried out for choosing the optimum therapy, evaluating therapy results and comparing multicentre results for better qualification in the therapy of the disease. In this study, 448 patients, whose surgery and follow-up was performed by the same correspondent surgeon between the years 1995 and 2003, were retrospectively analyzed. Age, presence of comorbidity, weight loss, emergency admission, high serum CEA and CA 19-9 levels, neighboring organ invasion, operation type, major morbidity, tumor size and type, lymph node metastases, venous and perineural invasion, Dukes' classification and local recurrence and distant metastasis during follow-up are found to be significant negative factors affecting prognosis of the CRC patient. Therapy results of the CRC are evaluated by survival times regardless of the therapy method selected for each individual. In our study we tried to find out negative prognostic factors by researching possible factors affecting disease free survival time for CRC. Since our understanding of factors that have an impact on prognosis increases, we are hoping to improve survival.en_US
dc.identifier.doi10.1007/s12262-010-0052-1en_US
dc.identifier.endpage248en_US
dc.identifier.issn0972-2068
dc.identifier.issue3en_US
dc.identifier.pmid23133256en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage243en_US
dc.identifier.urihttps://doi.org/10.1007/s12262-010-0052-1
dc.identifier.urihttps://hdl.handle.net/11454/43800
dc.identifier.volume72en_US
dc.identifier.wosWOS:000281319700015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofIndian Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColorectal canceren_US
dc.subjectPrognosisen_US
dc.subjectSurviveen_US
dc.titleNegative prognostic factors in colorectal carcinoma: An analysis of 448 patientsen_US
dc.typeArticleen_US

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