Electrochemical Monitoring of Interaction of Temozolamide with DNA by Graphene Oxide Modified Single-Use Electrodes

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dc.authoridErdem, Arzum/0000-0002-4375-8386
dc.authoridUNAL, DIDEM NUR/0000-0002-3300-138X
dc.authoridEksin, Ece/0000-0001-7175-2857
dc.authorscopusid55845006300
dc.authorscopusid57470955100
dc.authorscopusid57194853154
dc.authorscopusid7004459748
dc.authorwosidUnal, Didem Nur/AGJ-4973-2022
dc.authorwosidErdem, Arzum/X-1925-2019
dc.contributor.authorEksin, Ece
dc.contributor.authorIsin, Deniz
dc.contributor.authorUnal, Didem Nur
dc.contributor.authorErdem, Arzum
dc.date.accessioned2023-01-12T20:03:08Z
dc.date.available2023-01-12T20:03:08Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractGraphene oxide (GO) modified single-use pencil graphite electrodes (PGEs) were used for electrochemical monitoring of surface confined interaction between Temozolamide (TMZ) and calf thymus double stranded DNA (ctdsDNA). First, the PGE surface was activated by EDC/NHS (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxysuccinimide) as covalent agents (CA). Then, modification of GO was done onto the surface of chemically activated PGE surface to obtain CA-GO-PGEs. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy studies were used to establish the interfacial electron transfer of the electrodes. The optimization of experimental conditions was carried out via CV technique followed by electrochemical examination of the interaction of TMZ with ctdsDNA. (c) 2022 The Electrochemical Society (ECS). Published on behalf of ECS by IOP Publishing Limited.en_US
dc.description.sponsorshipTurkish Academy of Sciences (TUBA)en_US
dc.description.sponsorshipA.E. would like to express her gratitude to the Turkish Academy of Sciences (TUBA) as a Principal member for its partial support.en_US
dc.identifier.doi10.1149/1945-7111/ac4db1
dc.identifier.issn0013-4651
dc.identifier.issn1945-7111
dc.identifier.issn0013-4651en_US
dc.identifier.issn1945-7111en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85125503717en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1149/1945-7111/ac4db1
dc.identifier.urihttps://hdl.handle.net/11454/77662
dc.identifier.volume169en_US
dc.identifier.wosWOS:000754062100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElectrochemical Soc Incen_US
dc.relation.ispartofJournal Of The Electrochemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHplc Methoden_US
dc.subjectRat Plasmaen_US
dc.subjectTemozolomideen_US
dc.subjectHybridizationen_US
dc.subjectChitosanen_US
dc.subjectBehavioren_US
dc.subjectDrugen_US
dc.titleElectrochemical Monitoring of Interaction of Temozolamide with DNA by Graphene Oxide Modified Single-Use Electrodesen_US
dc.typeArticleen_US

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