Evaluation of Antioxidant, Antimicrobial and Antimutagenic Activity with Irritation Effects of Ceramium rubrum (Red Algae) Extract

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dc.contributor.authorGüner, Adem
dc.contributor.authorYavaşoğlu, Nefise Ülkü Karabay
dc.date.accessioned2020-12-01T12:33:20Z
dc.date.available2020-12-01T12:33:20Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study was conducted to evaluate antioxidant, antimutagenic and antimicrobial activities as well as irritation/toxicity efficacy of n-hexane, chloroform and methanol extracts of the red algae Ceramium rubrum C. Agardh (1881). While spectrophotometric methods were used for the determination of total phenol and flavonoid content, antioxidant activity was evaluated by DPPH assay. Antimicrobial and antimutagenic efficacy of extracts were determined by MIC method and Ames test, respectively. Also, HET-CAM test was used for irritation/toxicity of extracts. While methanol extract was found to have higher total flavonoid and phenolic contents than the other extracts and hexane showed higher antioxidant activity than other extracts. All extracts exerted moderate antimicrobial activity against tested microorganisms as 64–256 ?g/mL. However, extracts of the algae did not show any mutagenicity or irritation effect even at the highest concentration.en_US
dc.identifier.endpage287en_US
dc.identifier.issn2148-6905
dc.identifier.issn2148-6905
dc.identifier.issue4en_US
dc.identifier.startpage279en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TXpRME1EazJOZz09
dc.identifier.urihttps://hdl.handle.net/11454/66526
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Secondary Metaboliteen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject0-Belirleneceken_US
dc.titleEvaluation of Antioxidant, Antimicrobial and Antimutagenic Activity with Irritation Effects of Ceramium rubrum (Red Algae) Extracten_US
dc.typeArticleen_US

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