Vitamin D deficiency in pregnant women and their neonates in spring time in western Turkey

dc.contributor.authorHalicioglu, Oya
dc.contributor.authorAksit, Sadik
dc.contributor.authorKoc, Feyza
dc.contributor.authorAkman, Sezin A.
dc.contributor.authorAlbudak, Esin
dc.contributor.authorYaprak, Isin
dc.contributor.authorCoker, Isil
dc.contributor.authorColak, Ayfer
dc.contributor.authorOzturk, Can
dc.contributor.authorGulec, Ebru S.
dc.date.accessioned2019-10-27T21:34:44Z
dc.date.available2019-10-27T21:34:44Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractAlthough Turkey is located in a sunny region, vitamin D deficiency is still a serious health problem in pregnant women and their infants, especially among the low socioeconomic status Turkish population. This study was carried out in order to measure serum 25-hydroxyvitamin D3 [25(OH)D] concentrations of the pregnant women in the last trimester and in their neonates at delivery and to determine the factors associated with maternal serum 25(OH) D concentrations. Among the patients visiting the Ege Obstetrics and Gynecology Hospital in the period March to May 2008, 258 healthy pregnant women >= 37 weeks of gestation were included in this study. The information on different characteristics such as the number of pregnancies and births, nutritional status, vitamin and mineral support during gestation, educational status, clothing style and the economic level of the family was collected from women. Blood samples from the mothers and umbilical cord of the newborns were taken to measure 25(OH) D. The mean 25(OH) D concentrations of the mothers and their infants were 11.5 +/- 5.4 ng/mL and 11.5 +/- 6.8 ng/mL, respectively. We found a strong positive correlation between maternal serum and umbilical cord blood 25(OH) D concentrations (r = 0.651, P < 0.001). The concentration of 25(OH) D was <= 20 ng/mL in 233 mothers (90.3%) and <= 10 ng/mL in 130 mothers (50.4%). Maternal serum 25(OH) D concentrations related strongly to factors such as uncovered dressing style, sufficient consumption of dairy products and multivitamin use during gestation (P < 0.05). About half (52.7%) of these women had a covered dressing style. 25(OH) D concentrations of these covered dressing mothers and their infants were 9.7 +/- 5.1 ng/mL and 9.7 +/- 5.6 ng/mL, respectively, which were significantly lower compared with those of uncovered mothers and their babies (P < 0.001). This study showed that, despite a sunny environment, vitamin D deficiency and insufficiency are highly prevalent among the mothers and their neonates. This is generally due to the life style and nutritional status of the mothers. These findings suggest that much more effective vitamin D prophylaxis programmes should be implemented for pregnant women as well as for their babies.en_US
dc.description.sponsorshipMinistry of Health, Tepecik Teaching and Research Hospital, Association of Youth and Sports ClubIzmir Tepecik Training & Research Hospitalen_US
dc.description.sponsorshipThis study was supported financially by The Ministry of Health, Tepecik Teaching and Research Hospital, Association of Youth and Sports Club. We thank to all of biochemical laboratory staff for sample collection and testing.en_US
dc.identifier.doi10.1111/j.1365-3016.2011.01238.xen_US
dc.identifier.endpage60en_US
dc.identifier.issn0269-5022
dc.identifier.issue1en_US
dc.identifier.pmid22150708en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-3016.2011.01238.x
dc.identifier.urihttps://hdl.handle.net/11454/45675
dc.identifier.volume26en_US
dc.identifier.wosWOS:000298587400008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofPaediatric and Perinatal Epidemiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectvitamin D deficiencyen_US
dc.subjectpregnancyen_US
dc.subjectcord blooden_US
dc.subjectmaternal dress coveren_US
dc.subjectmaternal dieten_US
dc.subjectdairy productsen_US
dc.subjectvitamin supplementsen_US
dc.titleVitamin D deficiency in pregnant women and their neonates in spring time in western Turkeyen_US
dc.typeArticleen_US

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