Ion-selective membrane electrode for the determination of a novel phenylpiperazine antidepressant, nefazodone
Küçük Resim Yok
Tarih
2000
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The construction and performance characteristics of ion-selective membrane electrodes for a newly found phenylpiperazine antidepressant, Nefazodone (NFN), based on its ion-pair complexes with phos-photungstate (PT), tetraphenylborate (TPB), tungstosilicate (TS) and reineckate (RN) in a poly(vinyl chloride) (PVC) matrix are described. the best ion-selective electrode for determination of NFN contains NFN-PT as the active material. This electrode exhibits a Nernstian response (62.6 0.4 mV per decade) in the range 1.5 x $10^5$ to 1.0 x 410^{-2}$ M NFN.HCl in solutions. the selectivity of this electrode to NFN in the presence of a number of sugar molecules, cations and drugs is reported. the potentiometric standard addition method and the argentometric titration method are used to determine the NFN amount in pure solution.
Açıklama
Anahtar Kelimeler
Mühendislik, Kimya
Kaynak
Turkish Journal of Chemistry
WoS Q Değeri
Scopus Q Değeri
Cilt
24
Sayı
4
