Skip metastasis in non-small cell lung cancer: does it affect the prognosis?

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dc.contributor.authorAkcay, Onur
dc.contributor.authorAkcam, Tevfik Ilker
dc.contributor.authorKaya, Seyda Ors
dc.contributor.authorSamancilar, Ozgur
dc.contributor.authorCeylan, Kenan Can
dc.contributor.authorSevinc, Serpil
dc.contributor.authorUnsal, Saban
dc.date.accessioned2019-10-27T11:08:55Z
dc.date.available2019-10-27T11:08:55Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: This study aims to examine skip metastases in patients who had resection due to non-small cell lung cancer. Methods: A total of 111 patients (94 males, 17 females; mean age: 58.9 +/- 10.2 years; range 35 to 82 years) who were diagnosed with non-small cell lung cancer and in whom an ipsilateral mediastinal lymph node metastasis was detected based on the pathological examination of the R0 pulmonary resection samples between January 2005 and December 2011 in our clinic were retrospectively analyzed. The patients were divided into two groups: the skip metastasis group (sN2) (group 1, n=55) [N1(-), N2(+)] and non-skip ipsilateral mediastinal lymph node metastasis group (nsN2) (group 2, n=56) [N1(+), N2(+)]. Results: The median survival was 25 months and five-year overall survival rate was 13% for both study groups. Five-year overall survival rate was higher in group 1, compared to group 2 (20% vs. 7.4%, respectively), although the difference was not statistically significant (p=0.084). Conclusion: Our study results show that five-year overall survival rates of operable patients with skip metastases are higher than those without skip metastases, although the difference is not statistically significant.en_US
dc.identifier.doi10.5606/tgkdc.dergisi.2017.13168
dc.identifier.endpage234en_US
dc.identifier.issn1301-5680
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage230en_US
dc.identifier.urihttps://doi.org/10.5606/tgkdc.dergisi.2017.13168
dc.identifier.urihttps://hdl.handle.net/11454/32230
dc.identifier.volume25en_US
dc.identifier.wosWOS:000402620300010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayinciliken_US
dc.relation.ispartofTurk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMediastinal lymph nodeen_US
dc.subjectnon-small cell lung canceren_US
dc.subjectskip metastasisen_US
dc.titleSkip metastasis in non-small cell lung cancer: does it affect the prognosis?en_US
dc.typeArticleen_US

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