Neutrophil/Monocyte Ratio: A new predictor of inhospital mortality in patients with spontaneous ascites infections

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Tarih

2020

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: To determine the clinical features and in-hospital mortality predictors of spontaneous ascites infection (SAI).Materials and Methods: In this retrospective study, 496 patients with liver cirrhosis hospitalized at the gastroenterology clinic between 2015-2019 were screened. Of the 304 cases with ascites, 80 diagnosed with SAI were included in the study. Results: Spontoneus ascites infections (SAI) was detected in 80 (16.1%) of 496 hospitalized patients with cirrhosis. In cirrhotic patients with SAI, the most common reason for presentation to the hospital was altered mental status, which was observed in 26 (32.5%) patients. Thirty-one (38.8%) patients were diagnosed with spontaneous bacterial peritonitis, 41 (51.2%) with culture-negative neutrocytic ascites, eight (10%) with monomicrobial non-neutrocytic bacteria ascites. In-hospital mortality was observed in 25 (31.3%) patients, and one-year mortality rate was 35% with total 28 patients. A high MELD-Na score, history of SAI, presence of hepatic encephalopathy at the time of hospitalization, and a neutrophil/monocyte ratio of >9.1 were determined as the predictors of in-hospital mortality. A neutrophil/monocyte ratio of >9.1 predicted in-hospital mortality at 72% sensitivity and 62% specificity.Conclusion: Successfully predicting mortality in SAI, easily calculated by a hemogram examination, and providing inexpensive, effective and fast results, neutrophil/monocyte ratio presents as a useful marker.

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Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi

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Cilt

34

Sayı

3

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