Correlation of liver-to-spleen ratio, lung CT scores, clinical, and laboratory findings of COVID-19 patients with two consecutive CT scans

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dc.contributor.authorGuler, Ezgi
dc.contributor.authorUnal, Nalan Gulsen
dc.contributor.authorCinkooglu, Akin
dc.contributor.authorSavas, Recep
dc.contributor.authorKose, Timur
dc.contributor.authorPullukcu, Husnu
dc.contributor.authorOzutemiz, Ahmet Omer
dc.date.accessioned2020-12-01T11:57:51Z
dc.date.available2020-12-01T11:57:51Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose Given the lack of information about abdominal imaging findings and correlation with clinical features of COVID-19, we aimed to evaluate the changes in hepatic attenuation during the course of disease. Our aim was to correlate the liver-to-spleen ratio (L/S), clinical, laboratory findings, and lung CT scores of patients with COVID-19 who had two consecutive chest CTs. Methods A retrospective search was performed between March 1, 2020 and April 26, 2020 to identify patients who had positive RT-PCR tests and two unenhanced chest CTs. Scans that were obtained at hospital admission and follow-up were reviewed to assess L/S and lung CT scores. Patients were divided into two groups based on lung CT scores (non-progressive vs progressive). Patient demographics, laboratory findings, length of hospital stay, and survival were noted from electronic medical records. Results Twenty patients in the progressive group and 7 patients in the non-progressive group were identified. the mean L/S of the progressive group (1.13 +/- 0.3) was lower than that of the non-progressive group (1.21 +/- 0.29) at hospital admission but there was no significant difference between the two groups (p = 0.547). L/S at follow-up was significantly different between the groups as the mean L/S values of the progressive and non-progressive groups were 1.02 +/- 0.23 and 1.25 +/- 0.29, respectively (p = 0.009). L/S was negatively correlated with AST and ALT (r = - 0.46,p = 0.016 andr = - 0.534,p = 0.004, respectively). There were significant differences between the two groups in terms of WBC, neutrophil, lymphocyte, monocyte, and platelet counts that were obtained at hospital admission. Length of hospital stay was significantly longer in patients in the progressive group (p = 0.035). Conclusions Decrease in L/S may be observed in patients with elevated lung CT scores at follow-up. WBC, neutrophil, lymphocyte, monocyte, and platelet counts at hospital admission may predict the progression of COVID-19.en_US
dc.identifier.doi10.1007/s00261-020-02805-yen_US
dc.identifier.issn2366-004X
dc.identifier.issn2366-0058
dc.identifier.pmid33051758en_US
dc.identifier.scopus2-s2.0-85092532428en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00261-020-02805-y
dc.identifier.urihttps://hdl.handle.net/11454/61839
dc.identifier.wosWOS:000578102200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAbdominal Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronavirusen_US
dc.subjectMultidetector computed tomographyen_US
dc.subjectLaboratoryen_US
dc.subjectThoraxen_US
dc.subjectLiveren_US
dc.titleCorrelation of liver-to-spleen ratio, lung CT scores, clinical, and laboratory findings of COVID-19 patients with two consecutive CT scansen_US
dc.typeArticleen_US

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