Development of a Label Free IGE Sensitive Aptasensor Based on Electrochemical Impedance Spectrometry
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bentham Science Publ Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A sensitive aptamer based electrochemical biosensor to detect human immunoglobulin E (IgE) is presented in this study. 5' Biotin labeled 45 mer DNA aptamer sequence was immobilized onto streptavidin coated graphite surfaces. Interaction between human IgE and DNA aptamer was monitored by Electrochemical Impedance Spectrometry (EIS) in a 0.48nM detection limit of IgE. EIS analyses are based on electron transfer resistance (R(ct)) in the presence of 5mM [Fe(CN)(6)](3-/4-).
Açıklama
Anahtar Kelimeler
Aptamer, IgE, biosensor, electrochemical impedance spectrometry (EIS)
Kaynak
Combinatorial Chemistry & High Throughput Screening
WoS Q Değeri
Q1
Scopus Q Değeri
Q3
Cilt
13
Sayı
7
