Clinical significance of ASCUS and ASC-H cytological abnormalities: a six-year experience at a single center

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dc.contributor.authorDemirtas, G. S.
dc.contributor.authorAkman, L.
dc.contributor.authorDemirtas, O.
dc.contributor.authorHursitoglu, B. S.
dc.contributor.authorTerek, M. C.
dc.contributor.authorZekioglu, O.
dc.contributor.authorYilmaz, H.
dc.contributor.authorOzsaran, A. A.
dc.date.accessioned2019-10-27T22:29:50Z
dc.date.available2019-10-27T22:29:50Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: To evaluate colposcopic biopsy results of patients with cervical cytological findings of atypical squamous cells of undetermined significance (ASC-US) and atypical squamous cells with high-grade lesions that cannot be excluded (ASC-H). Materials and Methods: A retrospective evaluation of data from 358 patients, who had cervical cytological findings of ASC-US (n=335) and ASC-H (n=23), and had colposcopic assessments between 2005 and 2011. Results: Cervical biopsy results of patients diagnosed with ASC-US cytology (n=335) revealed cervical squamous cell carcinoma 0.9 % (n=3) at biopsy, cervical intraepithelial neoplasia 3 (ON 3) in 3.8 % (n=13), cervical intraepithelial neoplasia 2 (CIN 2) in 1.1 % (n=4), cervical intraepithelial neoplasia 1 (CIN 1) in 35.2 % (n=118), and benign lesions in 59% (n=197). Cervical biopsy results of patients diagnosed with ASC-H cytology (n=23) revealed CIN 3 at biopsy in 39.3% (n=9), CIN 2 in 21.7% (n=5), CIN 1 in 26% (n=6), carcinoma in situ in 8.7% (n=2), and squamous cell cancer in one patient (4.3%). Conclusion: The cytological diagnosis of ASC-US may lead to the diagnosis of cervical intraepithelial lesion of higher grades as well as cervical cancer and should be evaluated by colposcopic cervical biopsy.en_US
dc.identifier.endpage154en_US
dc.identifier.issn0392-2936
dc.identifier.issue2en_US
dc.identifier.pmid26050352en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage150en_US
dc.identifier.urihttps://hdl.handle.net/11454/51166
dc.identifier.volume36en_US
dc.identifier.wosWOS:000354003200010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisher7847050 Canada Incen_US
dc.relation.ispartofEuropean Journal of Gynaecological Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectASCUSen_US
dc.subjectASC-Hen_US
dc.subjectCervical cytologyen_US
dc.subjectColposcopyen_US
dc.titleClinical significance of ASCUS and ASC-H cytological abnormalities: a six-year experience at a single centeren_US
dc.typeArticleen_US

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