Comparison of short and long ovulation induction protocols used in ART applications according to the ovarian response and outcome of pregnancy

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dc.contributor.authorTavmergen E.
dc.contributor.authorTavmergen Göker E.N.
dc.contributor.authorSendag F.
dc.contributor.authorSendag H.
dc.contributor.authorLevi R.
dc.date.accessioned2019-10-27T00:24:01Z
dc.date.available2019-10-27T00:24:01Z
dc.date.issued2002
dc.departmentEge Üniversitesien_US
dc.description.abstractThis retrospective study was designed to determine whether there is any difference between short and long protocol ovulation induction with Gonadotropin Releasing Hormone agonist (GnRHa) and gonadotropins used in Assisted Reproductive Technology (ART) applications according to the number of retrieved oocytes, oocyte maturity, fertilization rates, embryo quality and the outcome of pregnancies. 240 cycles consisting of in vitro fertilization (IVF) cycles without andrologic factor and intracytoplasmic sperm injection (ICSI) cycles were evaluated. 112 cycles which were induced by short protocol GnRHa and Follicle Stimulating Hormone (FSH) + Human Menopausal Gonadotropin (HMG) combinations and 128 cycles which were induced by long protocol GnRHa and FSH + HMG combinations were compared according to the number of retrieved oocytes, cancellation rate of cycles, oocyte maturity, fertilization rates, embryo quality and pregnancy rates. The cancellation rate for short protocol cycles were found to be significantly higher than those with long protocol. The number of retrieved oocytes, mature oocytes and fertilized oocytes were also found significantly lower. The quality of embryos did not show any significant difference between these groups. The clinical pregnancy rates were evidently found to be high in the long protocol cycles. As a conclusion we have found that while the number of retrieved oocytes, mature oocytes, fertilized oocytes and clinical pregnancy rates were increasing, the cancellation rate of cycles were decreasing significantly in ART cycles induced by long protocol.en_US
dc.identifier.doi10.1007/PL00007494en_US
dc.identifier.endpage11en_US
dc.identifier.issn0932-0067
dc.identifier.issue1en_US
dc.identifier.pmid11998967en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage5en_US
dc.identifier.urihttps://doi.org/10.1007/PL00007494
dc.identifier.urihttps://hdl.handle.net/11454/22969
dc.identifier.volume266en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectARTen_US
dc.subjectGnRHaen_US
dc.subjectOvulation inductionen_US
dc.subjectPregnancy outcomeen_US
dc.titleComparison of short and long ovulation induction protocols used in ART applications according to the ovarian response and outcome of pregnancyen_US
dc.typeArticleen_US

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