Comparison of the preemptive MgSO4 and remifentanil on perioperative hemodynamics and postoperative pain in total abdominal hysterectomy [Total abdominal histerektomi operasyonlarinda preemptif MgSO4 ile remifentanilin hemodinami ve postoperatif agri üzerine etkilerinin karşilaştirilmasi]

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dc.contributor.authorGünüşen I.
dc.contributor.authorKaraman S.
dc.contributor.authorFirat V.
dc.contributor.authorUyar M.
dc.date.accessioned2019-10-27T00:10:39Z
dc.date.available2019-10-27T00:10:39Z
dc.date.issued2005
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Administration of analgesia prior to surgical stimulus has been proposed to inhibit sensitivity to surgery at the spinal level and has been referred to as preemptive analgesia. In our study we compared the effects of MgSO4 and remifentanil on intraoperative analgesie requirements and postoperative pain. Materials and Methods: Forty patients, ASA I-II, between 30-60 years age undergoing total abdominal hysteretomy were randomly assigned to two groups. Prior to induction Group M received 30 mg kg-1 iv MgSO4 and Group R received 1 µg kg iv bolus remifentanil. After same anaesthetic induction, during surgery group M received 10 mg kg -1 min-1 MgSO4 infusion and, group R received 0.25 µg kg-1 min-1 remifentanil infusion. Postoperatively all groups received patient control analgesia (PCA) morphine by a standard protocol. Results: No intraoperative change in haemodynamics was noted in the M group. There was no significant difference in heartrate (HR) between the groups but the remifentanil group was more hypotensive (p<0.05). The intraoperative analgesic requirement was not different between the groups. Postoperative pain scores, morphine consumption and rescue medication requirements were lower in the MgSO4 group while sedation scores and patient satisfaction were higher (p<0.05). Conclusion: We conclude that MgSO4 produces equivalant perioperative analgesia and improved intraoperative haemodynamic stability, when compared with remifentanil.en_US
dc.identifier.endpage306en_US
dc.identifier.issn1304-0871
dc.identifier.issn1304-0871en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage298en_US
dc.identifier.urihttps://hdl.handle.net/11454/22016
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHemodynamic stabilityen_US
dc.subjectMagnesiumen_US
dc.subjectPostoperative painen_US
dc.subjectPreemptive analgesiaen_US
dc.subjectRemifentanilen_US
dc.titleComparison of the preemptive MgSO4 and remifentanil on perioperative hemodynamics and postoperative pain in total abdominal hysterectomy [Total abdominal histerektomi operasyonlarinda preemptif MgSO4 ile remifentanilin hemodinami ve postoperatif agri üzerine etkilerinin karşilaştirilmasi]en_US
dc.typeArticleen_US

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