Comparison of the preemptive MgSO4 and remifentanil on perioperative hemodynamics and postoperative pain in total abdominal hysterectomy [Total abdominal histerektomi operasyonlarinda preemptif MgSO4 ile remifentanilin hemodinami ve postoperatif agri üzerine etkilerinin karşilaştirilmasi]
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aim: Administration of analgesia prior to surgical stimulus has been proposed to inhibit sensitivity to surgery at the spinal level and has been referred to as preemptive analgesia. In our study we compared the effects of MgSO4 and remifentanil on intraoperative analgesie requirements and postoperative pain. Materials and Methods: Forty patients, ASA I-II, between 30-60 years age undergoing total abdominal hysteretomy were randomly assigned to two groups. Prior to induction Group M received 30 mg kg-1 iv MgSO4 and Group R received 1 µg kg iv bolus remifentanil. After same anaesthetic induction, during surgery group M received 10 mg kg -1 min-1 MgSO4 infusion and, group R received 0.25 µg kg-1 min-1 remifentanil infusion. Postoperatively all groups received patient control analgesia (PCA) morphine by a standard protocol. Results: No intraoperative change in haemodynamics was noted in the M group. There was no significant difference in heartrate (HR) between the groups but the remifentanil group was more hypotensive (p<0.05). The intraoperative analgesic requirement was not different between the groups. Postoperative pain scores, morphine consumption and rescue medication requirements were lower in the MgSO4 group while sedation scores and patient satisfaction were higher (p<0.05). Conclusion: We conclude that MgSO4 produces equivalant perioperative analgesia and improved intraoperative haemodynamic stability, when compared with remifentanil.
Açıklama
Anahtar Kelimeler
Hemodynamic stability, Magnesium, Postoperative pain, Preemptive analgesia, Remifentanil
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
33
Sayı
4
