Ballard and new ballard scoring systems in the assessment of gestational age in preterm infants [Prematüre bebeklerde patent duktus arteriozusun tedavisinde enteral ibuprofen ve indometazinin etkinligi ve güvenilirligi]
dc.contributor.author | Akisü M. | |
dc.contributor.author | Ruhi Özyürek A. | |
dc.contributor.author | Dorak C. | |
dc.contributor.author | Parlar A. | |
dc.contributor.author | Kültürsay N. | |
dc.date.accessioned | 2019-10-27T00:25:11Z | |
dc.date.available | 2019-10-27T00:25:11Z | |
dc.date.issued | 2001 | |
dc.department | Ege Üniversitesi | en_US |
dc.description.abstract | This study was designed to investigate the efficacy and safety of enteral ibuprofen for the treatment of patent ductus arteriosus (PDA) and to compare it with enteral indomethacin. Twenty-three premature infants with gestational ages of less than 35 weeks with echocardiographically confirmed PDA were randomly assigned to receive either enteral indomethacin (3 × 0.2 mg/kg at 12 hour intervals) or enteral ibuprofen (1 × 10 mg/kg, followed by 5 mg/kg 24 and 48 hours later). PDA closed in eight of 11 patients (72%) from the indomethacin group and in 10 of 12 (83%) from the ibuprofen group in the first treatment. Five patients (three from indomethacin group, two from ibuprofen group) required a second treatment with the same drug. Ultimately, PDA closed in nine preterm infants from the indomethacin group (81%) and in 10 preterm infants from the ibuprofen group (83%). Ibuprofen patients had a better urinary output compared with the indomethacin group, an ibuprofen treatment was not associated with significant side effects. As a result, ibuprofen treatment seems to be as efficient as indomethacin in closing PDA in preterm infants, with fewer renal side effects. | en_US |
dc.identifier.endpage | 60 | en_US |
dc.identifier.issn | 0010-0161 | |
dc.identifier.issn | 0010-0161 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopusquality | Q4 | en_US |
dc.identifier.startpage | 56 | en_US |
dc.identifier.uri | https://hdl.handle.net/11454/23207 | |
dc.identifier.volume | 44 | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | tr | en_US |
dc.relation.ispartof | Cocuk Sagligi ve Hastaliklari Dergisi | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Ibuprofen | en_US |
dc.subject | Indomethacin | en_US |
dc.subject | Newborn | en_US |
dc.subject | Patent ductus arteriosus | en_US |
dc.title | Ballard and new ballard scoring systems in the assessment of gestational age in preterm infants [Prematüre bebeklerde patent duktus arteriozusun tedavisinde enteral ibuprofen ve indometazinin etkinligi ve güvenilirligi] | en_US |
dc.type | Article | en_US |