Ballard and new ballard scoring systems in the assessment of gestational age in preterm infants [Prematüre bebeklerde patent duktus arteriozusun tedavisinde enteral ibuprofen ve indometazinin etkinligi ve güvenilirligi]

dc.contributor.authorAkisü M.
dc.contributor.authorRuhi Özyürek A.
dc.contributor.authorDorak C.
dc.contributor.authorParlar A.
dc.contributor.authorKültürsay N.
dc.date.accessioned2019-10-27T00:25:11Z
dc.date.available2019-10-27T00:25:11Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study was designed to investigate the efficacy and safety of enteral ibuprofen for the treatment of patent ductus arteriosus (PDA) and to compare it with enteral indomethacin. Twenty-three premature infants with gestational ages of less than 35 weeks with echocardiographically confirmed PDA were randomly assigned to receive either enteral indomethacin (3 × 0.2 mg/kg at 12 hour intervals) or enteral ibuprofen (1 × 10 mg/kg, followed by 5 mg/kg 24 and 48 hours later). PDA closed in eight of 11 patients (72%) from the indomethacin group and in 10 of 12 (83%) from the ibuprofen group in the first treatment. Five patients (three from indomethacin group, two from ibuprofen group) required a second treatment with the same drug. Ultimately, PDA closed in nine preterm infants from the indomethacin group (81%) and in 10 preterm infants from the ibuprofen group (83%). Ibuprofen patients had a better urinary output compared with the indomethacin group, an ibuprofen treatment was not associated with significant side effects. As a result, ibuprofen treatment seems to be as efficient as indomethacin in closing PDA in preterm infants, with fewer renal side effects.en_US
dc.identifier.endpage60en_US
dc.identifier.issn0010-0161
dc.identifier.issn0010-0161en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage56en_US
dc.identifier.urihttps://hdl.handle.net/11454/23207
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofCocuk Sagligi ve Hastaliklari Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIbuprofenen_US
dc.subjectIndomethacinen_US
dc.subjectNewbornen_US
dc.subjectPatent ductus arteriosusen_US
dc.titleBallard and new ballard scoring systems in the assessment of gestational age in preterm infants [Prematüre bebeklerde patent duktus arteriozusun tedavisinde enteral ibuprofen ve indometazinin etkinligi ve güvenilirligi]en_US
dc.typeArticleen_US

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