Pooled analysis of 2,408 cases of acute adult purulent meningitis from Turkey

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dc.contributor.authorArda, Bilgin
dc.contributor.authorSipahi, Oguz Resat
dc.contributor.authorAtalay, Sabri
dc.contributor.authorUlusoy, Sercan
dc.date.accessioned2019-10-27T19:57:25Z
dc.date.available2019-10-27T19:57:25Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: The aim of this study was to systematically review the Turkish literature of acute adult purulent meningitis. Materials and Methods: The published series of three national databases and two international databases were searched to perform the review. In addition to the databases, abstracts of congresses held between 1994 and 2003 by the Turkish Clinical Microbiology and Infectious Diseases Association, Turkish Microbiology Association, and the Antibiotic and Chemotherapy Association were searched for reports about acute purulent meningitis. Results: Data for 2,408 patients with a diagnosis of acute purulent meningitis were obtained from 30 reports. In terms of clinical findings, 1,254 of 1,570 (79.8%) had fever (> 38 degrees C), 1,408 of 1,595 (88.2%) headache, 1,403 of 1,562 (89.8%) stiffness of the neck, and 649 of 784 (82.7%) leukocytosis (> 10,000/mm(3)). Cerebrospinal fluid culture yielded a pathogen in 873 of 2,260 (38.6%) patients. The most common pathogen was Streptococcus pneumoniae, followed by Neisseria meningitidis and Staphylococcus aureus. Overall mortality was 425 of 2,408 (17.6%). Pathogen-specific mortality was 60 of 202 (29.7%) for S. pneumoniae and 6 of 100 (6%) for N. meningitidis. Conclusion: Meningitis is a serious, life-threatening disease. More preventive measures should be sought to further decrease the mortality and morbidity related to acute purulent meningitis. Copyright (c) 2007 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000109595en_US
dc.identifier.endpage79en_US
dc.identifier.issn1011-7571
dc.identifier.issue1en_US
dc.identifier.pmid18059106en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage76en_US
dc.identifier.urihttps://doi.org/10.1159/000109595
dc.identifier.urihttps://hdl.handle.net/11454/40948
dc.identifier.volume17en_US
dc.identifier.wosWOS:000251438100013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectbacterial meningitis, Turkeyen_US
dc.subjectepidemiologyen_US
dc.subjectsystematic reviewen_US
dc.subjectpooled analysisen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectmortalityen_US
dc.titlePooled analysis of 2,408 cases of acute adult purulent meningitis from Turkeyen_US
dc.typeArticleen_US

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