Impact of bupivacaine injection to trocar sites on postoperative pain following laparoscopic hysterectomy: Results from a prospective, multicentre, double-blind randomized controlled trial

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Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objectives: Laparoscopic surgery has numerous advantages over open surgery in view of postoperative pain. in this context, to elevate its benefits and patient satisfaction, different pain management interventions have been used so far. This study aimed to evaluate the effect of bupivacaine injection to trocar sites following laparoscopic hysterectomy for the management of postoperative pain. Study design: in this study, patients were randomized into two groups (56 cases; 52 controls). A single injection of bupivacaine (0.5 %, 5 mg/mL) was introduced to trocar sites under subcutaneous tissue at a dose of 4 ml for the umbilicus and 2 ml for each 5-mm ancillary trocar site in the study group. No bupivacaine was administered to the control group. the primary aim was to measure differences in 2-h postoperative numerical rating scale (NRS) pain scores between the two groups. the secondary aims were to evaluate differences between 1-, 4-, 6-, 24 and 48-h postoperative NRS pain scores, surgical complications, estimated blood loss, duration of operation and analgesic consumption. Results: the number of postoperative rescue doses of analgesics was found to be lower in the study group compared to the control group (median of 2 vs. 4; p < 0.01). the 1-, 4-, 6-, 24and 48-hour postoperative NRS pain scores were also found to be lower in the study group compared to the control group (p < 0.01 at each follow-up). the mean duration of surgery and uterus removal, as well as the estimated blood loss, were not significantly different between the two groups. Conclusions: the present study suggests that bupivacaine injection to trocar sites is an effective and safe method for reducing pain following laparoscopic hysterectomy. (C) 2020 Elsevier B.V. All rights reserved.

Açıklama

Anahtar Kelimeler

Total laparoscopic hysterectomy, Local anaesthetics, Bupivacaine, Postoperative pain

Kaynak

European Journal of Obstetrics & Gynecology and Reproductive Biology

WoS Q Değeri

Q3

Scopus Q Değeri

N/A

Cilt

252

Sayı

Künye