Demographic, clinical, laboratory, ultrasonographic, and cytological features of patients with Hashimoto's thyroiditis: results of a university hospital of 769 patients in Turkey

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dc.contributor.authorErdogan, Mehmet
dc.contributor.authorErdem, Nihat
dc.contributor.authorCetinkalp, Sevki
dc.contributor.authorOzgen, Ahmet Gokhan
dc.contributor.authorSaygili, Fusun
dc.contributor.authorYilmaz, Candeger
dc.contributor.authorTuzun, Mehmet
dc.contributor.authorKabalak, Taylan
dc.date.accessioned2019-10-27T21:19:07Z
dc.date.available2019-10-27T21:19:07Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractWe investigated the demographic and clinical features of patients with Hashimoto's thyroiditis who had been diagnosed and treated in Ege University, the main referral center in the Aegean region of Turkey. Medical records of patients who had been followed in the endocrinology clinic of Ege University were retrospectively evaluated. Patients who had been diagnosed as having any thyroid disorder were determined. Patients with Hashimoto's thyroiditis were selected among those patients. Seven hundred and sixty-nine patients fulfilled diagnostic criteria for Hashimoto's thyroiditis (725 females, 44 males; mean age 41.76 +/- A 12.49 years). 62.7% of patients were between 30 and 50 years of age. 53.3% of females and 63.6% of males had diffuse enlargement of the thyroid gland. TSH level was above 4.0 IU/l in 25.6% of females and 27.4% of males. Anti-tyroglobulin antibody was positive in 92% of females and 93.2 % of males. Anti-thyroid peroxidase antibody was positive in 98.4 % of females (713 patients) and 100% of males. Thyroid ultrasonography demonstrated single nodule in 52.2% and multiple nodules in 11.3% of female patients; and single nodule 32% and multiple nodules in 20% of male patients. Fine-needle aspirations of the nodules were performed in 207 patients, and none of those biopsies was diagnosed as malignant. Women with suspicious biopsis were operated. After surgery, we found that, 2% (n = 4) of patients with FNAC diagnosis of suspicious biopsies were papillary carcinoma and the other patients (3% (n = 6)) were lymphocytic thyroiditis. Age and sex distribution and laboratory findings of our patients were comparable to the previous reports. Nodule formation was the most common ultrasonographic finding in our patients, probably due to pseudonodularity. We found four women patients with thyroid cancer in our population.en_US
dc.identifier.doi10.1007/s12020-009-9258-zen_US
dc.identifier.endpage490en_US
dc.identifier.issn0969-711X
dc.identifier.issue3en_US
dc.identifier.pmid19856136en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage486en_US
dc.identifier.urihttps://doi.org/10.1007/s12020-009-9258-z
dc.identifier.urihttps://hdl.handle.net/11454/44097
dc.identifier.volume36en_US
dc.identifier.wosWOS:000271501700021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofEndocrineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHashimoto's thyroiditisen_US
dc.subjectDemographic and clinical featuresen_US
dc.titleDemographic, clinical, laboratory, ultrasonographic, and cytological features of patients with Hashimoto's thyroiditis: results of a university hospital of 769 patients in Turkeyen_US
dc.typeArticleen_US

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