A comprehensive analysis of subungual melanomas in a tertiary center: Is amputation outmoded?

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dc.contributor.authorMammadov, Vasif
dc.contributor.authorYeğin, Mehmet Emre
dc.contributor.authorTopaloglu, Ege
dc.contributor.authorGur, Ersin
dc.contributor.authorTiftikcioğlu, Yigit Özer
dc.contributor.authorGürler, Tahir
dc.date.accessioned2024-08-25T18:38:16Z
dc.date.available2024-08-25T18:38:16Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Subungual melanoma is a rare entity. The literature lacks information about its treatment. Alternative treatments exist; amputation or wide local excision (WLE), with or without sentinel lymph node biopsy (SLNB). This study discusses the classical approach for subungual melanoma and compares it with the alternatives. Materials and Methods: A retrospective analysis of subungual melanoma cases between 2008 and 2020 in a tertiary center was done. Results: Thirteen patients were found to have subungual melanoma. Amputation and SLNB were the treatment of choice in 12 patients with invasive diseases. In one patient with a in-situ illness, WLE and SLNB were applied. Mean Breslow thickness was found to be 4.2 mm. The preoperative evaluation showed no signs of metastases in 10 patients, and these patients had SLNB. Two patients had pathological lymph node characteristics in the preoperative evaluation and had elective lymph node dissection (ELND) without SLNB. The mean follow-up was six years, and seven patients died during the follow-ups. Six patients died of natural causes, while one died of systemic disease. Conclusion: Subungual melanoma is a disease that can be controlled with amputation. WLE can be used in in-situ melanomas, but amputation is still a good choice for invasive illnesses.en_US
dc.identifier.endpage138en_US
dc.identifier.issn1016-9113
dc.identifier.issn2147-6500
dc.identifier.issue1en_US
dc.identifier.startpage134en_US
dc.identifier.trdizinid1158998en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1158998
dc.identifier.urihttps://hdl.handle.net/11454/100941
dc.identifier.volume62en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofEge Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectAmputationen_US
dc.subjectlymph node dissectionen_US
dc.subjectmelanomaen_US
dc.subjectneoplasm metastasisen_US
dc.subjectsentinel lymph node.[Amputasyonen_US
dc.subjectlenf nodu diseksiyonuen_US
dc.subjectmelanomen_US
dc.subjectneoplazi metastazıen_US
dc.subjectsentinel lenf nodu.en_US
dc.titleA comprehensive analysis of subungual melanomas in a tertiary center: Is amputation outmoded?en_US
dc.typeArticleen_US

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