Improved neonatal prognosis following restriction in the number of transferred embryos in assisted reproduction - single center yearly comparison from Turkey

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dc.contributor.authorKultursay, N.
dc.contributor.authorKoroglu, O. A.
dc.contributor.authorUygur, O.
dc.contributor.authorTerek, D.
dc.contributor.authorTannverdi, S.
dc.contributor.authorAkisu, M.
dc.contributor.authorYalaz, M.
dc.date.accessioned2019-10-27T22:29:30Z
dc.date.available2019-10-27T22:29:30Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To evaluate the impact of new legislation for assisted reproductive technology (ART) restricting the number of transferred embryos on neonatal prognosis of infants born after infertility treatments. Materials and Methods: Neonatal records of all live born infants in Ege University Maternity Ward were reviewed for 2006 and 2012. Neonatal outcome measures such as birth weight (BW), gestational age (GA), preterm birth (PTB), very low birth weight (VLBW), and neonatal intensive care unit (NICU) admission were evaluated. Results: Compared to 2006 percentage of newborns conceived by medically assisted reproduction (MAR) decreased from 14.6% to 5% in all live births, from 23.8% to 8.2% in NICU patients in 2012. The number of fetuses in the last pregnancy, frequency of intrauterine reductions, spontaneous pregnancy losses, antenatal bleeding, and premature delivery decreased. Percentage of multiples among MAR newborns (31.7% vs. 55.7%), twins from 51.4% to 30.9%, triplets from 4.3% to 0.8% all decreased significantly. Mean BW and gestational age increased resulting in decreased frequency of PTB and VLBW. Consequently Level 3 NICU admission rate significantly decreased from 44.3% to 22%. Conclusion: The new ART legislation in Turkey resulted in decreased rate of multiple births, prematurity and related complications, and NICU admissions in MAR newborns. However the twin rates are still high. Since uncontrolled ovulation stimulation and intrauterine insemination techniques are also associated with multiple births and unfavorable neonatal outcomes, these procedures deserve close monitorization.en_US
dc.identifier.endpage447en_US
dc.identifier.issn0390-6663
dc.identifier.issue4en_US
dc.identifier.pmid26411208en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage442en_US
dc.identifier.urihttps://hdl.handle.net/11454/51113
dc.identifier.volume42en_US
dc.identifier.wosWOS:000359512600009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMedically assisted reproductionen_US
dc.subjectNewbornen_US
dc.subjectMultipleen_US
dc.subjectMorbidityen_US
dc.subjectLegislationen_US
dc.subjectTurkeyen_US
dc.titleImproved neonatal prognosis following restriction in the number of transferred embryos in assisted reproduction - single center yearly comparison from Turkeyen_US
dc.typeArticleen_US

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