Cervical Spondylotic Myelopathy: Natural Course and the Value of Diagnostic Techniques - WFNS Spine Committee Recommendations

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dc.contributor.authorZileli, Mehmet
dc.contributor.authorBorkar, Sachin A.
dc.contributor.authorSinha, Sumit
dc.contributor.authorReinas, Rui
dc.contributor.authorAlves, Oscar L.
dc.contributor.authorKim, Se-Hoon
dc.contributor.authorParthiban, Jutty
dc.date.accessioned2020-12-01T12:09:25Z
dc.date.available2020-12-01T12:09:25Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.descriptionZileli, Mehmet/0000-0002-0448-3121en_US
dc.description.abstractObjective: This study presents the results of a systematic literature review conducted to determine most up-to-date information on the natural outcome of cervical spondylotic myelopathy (CSM) and the most reliable diagnostic techniques. Methods: A literature search was performed for articles published during the last 10 years. Results: the natural course of patients with cervical stenosis and signs of myelopathy is quite variable. in patients with no symptoms, but significant stenosis, the risk of developing myelopathy with cervical stenosis is approximately 3% per year. Myelopathic signs are useful for the clinical diagnosis of CSM. However, they are not highly sensitive and may be absent in approximately one-fifth of patients with myelopathy. the electrophysiological tests to be used in CSM patients are motor evoked potential (MEP), spinal cord evoked potential, somatosensory evoked potential, and electromyography (EMG). the differential diagnosis of CSM from other neurological conditions can be accomplished by those tests. MEP and EMG monitoring are useful to reduce C5 root palsy during CSM surgery. Notable spinal cord T2 hyperintensity on cervical magnetic resonance imaging (MRI) is correlated with a worse outcome, whereas lighter signal changes may predict better outcomes. T1 hypointensity should be considered a sign of more advanced disease. Conclusion: the natural course of CSM is quite variable. Signal changes on MRI and some electrophysiological tests are valuable adjuncts to diagnosis.en_US
dc.identifier.doi10.14245/ns.1938240.120en_US
dc.identifier.endpage402en_US
dc.identifier.issn2586-6583
dc.identifier.issn2586-6591
dc.identifier.issue3en_US
dc.identifier.pmid31607071en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage386en_US
dc.identifier.urihttps://doi.org/10.14245/ns.1938240.120
dc.identifier.urihttps://hdl.handle.net/11454/63444
dc.identifier.volume16en_US
dc.identifier.wosWOS:000488270600003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Spinal Neurosurgery Socen_US
dc.relation.ispartofNeurospineen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCervical spondylotic myelopathyen_US
dc.subjectElectrophysiologyen_US
dc.subjectMyelopathic signsen_US
dc.subjectMR signal intensityen_US
dc.subjectIntraoperative monitoringen_US
dc.subjectMagnetic resonance imagingen_US
dc.titleCervical Spondylotic Myelopathy: Natural Course and the Value of Diagnostic Techniques - WFNS Spine Committee Recommendationsen_US
dc.typeReview Articleen_US

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