A new recommendation for febrile urinary tract infection in children aged 2-24 months: Tepecik UTI Guideline-2

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dc.authoridkoyun, begum/0000-0002-7874-0215
dc.authoridArslansoyu Camlar, Secil/0000-0002-2402-0722
dc.authorscopusid58054556300
dc.authorscopusid55880499700
dc.authorscopusid35114625600
dc.authorscopusid7801347643
dc.authorscopusid8294173700
dc.authorscopusid26428015700
dc.authorscopusid47461055000
dc.contributor.authorCezayir, Begum Koyun
dc.contributor.authorYavascan, Onder
dc.contributor.authorAlaygut, Demet
dc.contributor.authorDemir, Belde Kasap
dc.contributor.authorMutlubas, Fatma
dc.contributor.authorCamlar, Secil Arslansoyu
dc.contributor.authorAlparslan, Caner
dc.date.accessioned2024-08-25T18:32:24Z
dc.date.available2024-08-25T18:32:24Z
dc.date.issued2022
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: Urinary tract infections (UTIs) represent a common febrile illness in infancy. The study compared two UTI guidelines in terms of number of imaging studies, presence of parenchymal damage and radiation exposure in patients with the first febrile UTI between 2 and 24months of age. Method: The results of Tepecik UTI Guideline-1 used until 2012 (Group 1, n=105) were retrospectively compared with Tepecik UTI Guideline-2 (Group 2) used after 2013. In Group 1, urinary tract ultrasonography (US), dimercaptosuccinic acid (DMSA) and voiding cystourethrography (VCUG) were made in all patients. In Group 2, if the US result was abnormal, patients were evaluated with VCUG and DMSA. If the US was normal, only DMSA was performed. If the DMSA was abnormal, the VCUG was undergone (n: 43, 40.9%). Results: The abnormal VCUG detection rate was 69.2% in Group 1 and 30.8% in Group 2 (p=0.09). Sensitivity and specificity of US in the diagnosis of vesicoureteral reflux (VUR) was 15.9% and 96.7% in Group 1 and 61.5% and 70.5% in Group 2, respectively. Abnormal DMSA findings were observed among 33.3% (Groups 1) and 66.7% (Groups 2) subjects, respectively (p>0.05). The median radiation exposure (500mrem) of patients in Group 1 was statistically significantly higher than those in Group 2 (200mrem) (p<0.001). Conclusion: The VCUG should not be the first examination to be considered in such patients. We think that Tepecik UTI Guideline-2 reduces unnecessary invasive procedure and radiation exposure and not missed VUR in the management of children with UTI at 2-24months. Needs prospective follow-up studies before considering this recommendation.en_US
dc.identifier.doi10.1093/tropej/fmac109
dc.identifier.issn0142-6338
dc.identifier.issn1465-3664
dc.identifier.issue1en_US
dc.identifier.pmid36625359en_US
dc.identifier.scopus2-s2.0-85145956770en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1093/tropej/fmac109
dc.identifier.urihttps://hdl.handle.net/11454/100222
dc.identifier.volume69en_US
dc.identifier.wosWOS:000911526200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofJournal of Tropical Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectfebrile urinary tract infectionen_US
dc.subjectmfancyen_US
dc.subjectultrasonographyen_US
dc.subjectVCUGen_US
dc.subjectDMSA scintigraphyen_US
dc.subjectVoiding Cystourethrographyen_US
dc.subjectFollow-Upen_US
dc.titleA new recommendation for febrile urinary tract infection in children aged 2-24 months: Tepecik UTI Guideline-2en_US
dc.typeArticleen_US

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