The effects of branched-chain amino acids on the oxygen consumption in patients with metabolic stress [Metabolik stresli hastalarda dallanmis zincirli aminoasitlerin oksijen tuketimine etkisi]

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dc.contributor.authorSakarya M.
dc.contributor.authorMert S.
dc.contributor.authorMoral A.R.
dc.date.accessioned2019-10-27T00:26:59Z
dc.date.available2019-10-27T00:26:59Z
dc.date.issued1999
dc.departmentEge Üniversitesien_US
dc.description.abstractIn recent years, there has been a much controversy about the feasibility of amino acid solutions with a high content of branched-chain amino acids (BCAA: leucine, isoleucine, valine) in fields of hepatic failure, trauma, obtaining a better nitrogen balance, low morbidity and low mortality. The aim of this study was to establish the effects of BCAA infusions on the oxygen consumption (VO2) in patients with metabolic stress. We studied nine patients who were mechanically ventilated suffering from acute respiratory failure. Muscle relaxants, sedation and volum controlled mechanical ventilatory support were applied to all patients. Daily energy supply was obtained with standard enteral formulas 1 kcal/mL. In addition to daily energy requirement, 0,5 g/kg amino acid solution which contains % 45 BZAA was infused parenterally in 6 hours. Before (I) and after (II) 6 hours infusion VO2 were calculated with thermodilution technique via pulmonary arterial catheter. Wilcoxon was used for statistically comparisons. We conclude that, although the statistical difference was non-significant between two measurements there seems to be a relative increase of VO2 consumption with the use of BCAA and this may be important in the ICU for critically ill patients with poor oxygen supply.en_US
dc.identifier.endpage296en_US
dc.identifier.issn1016-5150
dc.identifier.issn1016-5150en_US
dc.identifier.issue6en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage293en_US
dc.identifier.urihttps://hdl.handle.net/11454/23469
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBranched-chain amino acidsen_US
dc.subjectMetabolic stressen_US
dc.subjectOxygen consumptionen_US
dc.titleThe effects of branched-chain amino acids on the oxygen consumption in patients with metabolic stress [Metabolik stresli hastalarda dallanmis zincirli aminoasitlerin oksijen tuketimine etkisi]en_US
dc.typeArticleen_US

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