In vitro activity of Arbutus unedo against Leishmania tropica promastigotes.

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dc.contributor.authorKivçak B.
dc.contributor.authorMert T.
dc.contributor.authorErtabaklar H.
dc.contributor.authorBalcioglu I.C.
dc.contributor.authorOzensoy Töz S.
dc.date.accessioned2019-10-26T23:55:21Z
dc.date.available2019-10-26T23:55:21Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractPentavalent antimonials are the first choice for the treatment of anthroponotic cutaneous leishmaniasis (ACL) in health centers in Turkey, however in rural areas, traditional plants may be preferred for the treatment of lesions. In recent years a number of papers are published related to the natural products especially plant derivates. Our aim is to investigate the antileishmanial effect of Arbutus unedo which is a wild plant mainly grown in maquis and rocky places of the seabord in South Europe. In the present study, the ethanolic, water and n-hexane extracts from the leaves of Arbutus unedo were originally tested in vitro against Leishmania tropica promastigotes. The ethanol extract of Arbutus unedo leaves at the concentrations of 100, 250, 500 microg/ml were found to be more effective than the other extracts (p:0.000). Our study showed that the ethanolic extract of Arbutus unedo leaves can be a promising antileishmanial agent and further experiments are needed.en_US
dc.identifier.endpage115en_US
dc.identifier.issn1300-6320
dc.identifier.issue2en_US
dc.identifier.pmid19598085en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage114en_US
dc.identifier.urihttps://hdl.handle.net/11454/20612
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTürkiye parazitolojii dergisi / Türkiye Parazitoloji Dernegi = Acta parasitologica Turcica / Turkish Society for Parasitologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleIn vitro activity of Arbutus unedo against Leishmania tropica promastigotes.en_US
dc.typeArticleen_US

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