Henoch-Schönlein purpura and IgA nephropathy occuring in one patient: Case report

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dc.contributor.authorKeskinoğlu, Ahmet
dc.contributor.authorMir, Sevgi
dc.contributor.authorKabasakal, Caner
dc.contributor.authorCura, Alphan
dc.contributor.authorBaşdemir, Gülçin
dc.date.accessioned2020-12-01T12:14:19Z
dc.date.available2020-12-01T12:14:19Z
dc.date.issued1998
dc.departmentEge Üniversitesien_US
dc.description.abstractHenoch-Schönlein Purpura is characterized by the involvement of skin, gut, joints and kidneys. IgA nephropathy is a renal disorder characterized by hematuria. A 6-year-old-male was referred with gross hematuria, abdominal pain, and joint pain following a sore throat. He had purpuric skin lessions with normal renal function. Investigation revealed macroscopic hematuria, mild proteinuria, elevated IgA level, normal C3 level and negative CRP. Renal biopsy revealed a mesangiocap-illary glomerulonephritis with IgA and C3 granular deposits in the mesangial area. It was grade II HSP according to WHO'S classification. During the follow up he remained well for 2 years with microscopic hematuria. During the next 2 years he had no proteinuria or hematuria. At the age of 10 years he developed painless gross hematuria without the involvement of the other systems. Laboratory findings showed normal renal function, macroscopic hematuria and slight proteinuria. IgA levels were elevated. Skin biopsy has no deposits. in the renal biopsy by light microscopy glomeruli have slight mesangial hyper-cellularity and on immunofluorescent granular, predominantly IgA and C3 deposits. It was grade II IgA nephropathy. Our case, who initially developed Henoch-Schönlein purpura and 4 years later developed biopsy proven-lgA nephropathy, sug-gested the hypotesis of common pathogenesis for these conditions.en_US
dc.identifier.endpage79en_US
dc.identifier.issn1017-7698
dc.identifier.issue3-4en_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TlRNek1EQT0
dc.identifier.urihttps://hdl.handle.net/11454/63825
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedical Journal of Ege Universityen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenel ve Dahili Tıpen_US
dc.titleHenoch-Schönlein purpura and IgA nephropathy occuring in one patient: Case reporten_US
dc.typeOtheren_US

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