Platelet-activating factor levels in term and preterm human milk

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dc.contributor.authorAkisu, M
dc.contributor.authorKultursay, N
dc.contributor.authorOzkayin, N
dc.contributor.authorCoker, I
dc.contributor.authorHuseyinov, A
dc.date.accessioned2019-10-27T11:51:33Z
dc.date.available2019-10-27T11:51:33Z
dc.date.issued1998
dc.departmentEge Üniversitesien_US
dc.description.abstractIt is well known that necrotizing enterocolitis (NEC) is less frequent in newborns being fed human breast milk. Since recent studies indicated that platelet-activating factor (PAF) plays an important role in pathogenesis of NEC, this study was conducted to investigate the PAF levels in human milk. Colostrum and mature human milk (samples obtained in the third week) of three groups of mothers were investigated. The first group had given birth within less than 32 weeks, the second between 33-37 weeks and the third group after 38 weeks of gestation. The PAF levels in colostrum of all three groups were similar (0.95 +/- 0.57, 1.05 +/- 0.52 and 1.19 +/- 0.64 ng/ml, respectively). Mature human milk in groups I and II had similar PAF levels (1.16 +/- 0.54 and 1.21 +/- 0.60 ng/ml, respectively), however, mature human milk in group III had a significantly higher PAF concentration (2.04 +/- 0.59 ng/ml) than both groups' levels. However, this phenomenon by itself does not explain the protective effect of human milk against NEC.en_US
dc.identifier.doi10.1159/000014036en_US
dc.identifier.endpage293en_US
dc.identifier.issn0006-3126
dc.identifier.issue4en_US
dc.identifier.pmid9701651en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage289en_US
dc.identifier.urihttps://doi.org/10.1159/000014036
dc.identifier.urihttps://hdl.handle.net/11454/34582
dc.identifier.volume74en_US
dc.identifier.wosWOS:000075704200005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofBiology of the Neonateen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectplatelet-activating factoren_US
dc.subjecthuman milken_US
dc.subjectbreast milken_US
dc.subjectnecrotizing enterocolitisen_US
dc.subjectnewbornen_US
dc.titlePlatelet-activating factor levels in term and preterm human milken_US
dc.typeArticleen_US

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