Antimicrobial activity screening of a series of taurine derivatives

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dc.contributor.authorAkgül, Özlem
dc.contributor.authorAkgünlü, Çağlar
dc.contributor.authorBiler, Hatice
dc.contributor.authorAteş, Ayşegül
dc.contributor.authorErmertcan, Şafak
dc.date.accessioned2023-01-12T20:29:12Z
dc.date.available2023-01-12T20:29:12Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractIn this study, a series of taurinamide derivatives 1–18 were assessed for their in vitro antimicrobial activity. Enterococcus faecalis, which is the third most commonly isolated nosocomial pathogen among hospital infections, was found to be more susceptible to the tested compounds than other pathogens. Two of the tested compounds, 1 and 18, showed promising activity against E. faecalis, with minimal inhibitory concentrations (MICs) of 128 and 64 µg/mL, respectively. On the other hand, compound 3 was distinguished from other compounds by its better activity against G(?) Escherichia coli bacteria, with a MIC of 512 ?g/mL. None of the compounds displayed better activity than the standard drugs Ciprofloxacin and Fluconazole.en_US
dc.identifier.doi10.17776/csj.989570
dc.identifier.endpage788en_US
dc.identifier.issn2587-2680
dc.identifier.issn2587-246X
dc.identifier.issue4en_US
dc.identifier.startpage781en_US
dc.identifier.trdizinid1110508en_US
dc.identifier.urihttps://doi.org/10.17776/csj.989570
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1110508
dc.identifier.urihttps://hdl.handle.net/11454/80359
dc.identifier.volume42en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofCumhuriyet Science Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAntimicrobial activity screening of a series of taurine derivativesen_US
dc.typeArticleen_US

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