The Beneficial Effect of Exercise and Vitamin D Supplementation on Comorbidities Associated with Systemic Lupus Erythematosus

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dc.authoridOzkeskin, Mehmet/0000-0002-6892-0108
dc.contributor.authorGokcek, Ozden Canbay
dc.contributor.authorOzkeskin, Mehmet
dc.contributor.authorBaser, Miray
dc.date.accessioned2024-08-31T07:46:39Z
dc.date.available2024-08-31T07:46:39Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Systemic lupus erythematosus (SLE) is a multisystem chronic autoimmune disease characterized by recurrent and relapsing attacks that may affect the locomotor system as well as the liver and kidneys. Vitamin D deficiency is thought to playAa role in the pathogenesis of SLE. ATherefore, the primary aim of this literature review is to determine the role of vitamin D deficiency on SLE symptoms. The secondary aim is to explain the benefits of exercise on SLE-related comorbidities. Methods: A comprehensive literature search on SLE symptoms, biochemistry, and pathophysiology was conducted via Google Scholar. The impact of exercise on comorbidities associated with SLE was examined. Results: The precise etiology of the disease remains elusive, although there is mounting evidence that vitamin D deficiency is associated with symptoms of SLE. In addition to pharmacological treatment for the involvement of the locomotor system in SLE patients, physiotherapy applications are also included. This review presents evidence of the positive effects of exercise on pain, fatigue, and sleep problems caused by disease-related or side effects of pharmacological applications used in the treatment of SLE patients. Conclusions: It is not possible to correct the symptoms of SLE associated with vitamin D deficiency by means of vitamin D supplementation alone. At this juncture, it is hypothesized that exercise may offer potential benefits in correcting vitamin D deficiency. AConsequently, exercise exerts a beneficial influence on the comorbidities associated with SLE. AFuture studies should be planned to establish an appropriate exercise prescription for SLE.en_US
dc.identifier.doi10.18521/ktd.1356975
dc.identifier.endpage204en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage199en_US
dc.identifier.trdizinid1246571en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.1356975
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1246571
dc.identifier.urihttps://hdl.handle.net/11454/104160
dc.identifier.volume16en_US
dc.identifier.wosWOS:001272220200009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDuzce Univ, Fac Medicineen_US
dc.relation.ispartofKonuralp Tip Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectSystemic Lupus Erythematosusen_US
dc.subjectExerciseen_US
dc.subjectFatigueen_US
dc.subjectPainen_US
dc.subjectSleep Disordersen_US
dc.subjectVitamin Den_US
dc.titleThe Beneficial Effect of Exercise and Vitamin D Supplementation on Comorbidities Associated with Systemic Lupus Erythematosusen_US
dc.typeReview Articleen_US

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