Action plan to regain unnecessary deferred blood donors due to malaria risk in Turkey

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dc.contributor.authorDegirmenci A.
dc.contributor.authorDöşkaya M.
dc.contributor.authorCaner A.
dc.contributor.authorNergis Ş.
dc.contributor.authorGül K.
dc.contributor.authorAydinok Y.
dc.contributor.authorErtop T.
dc.contributor.authorAksoy N.
dc.contributor.authorKorkmaz M.
dc.contributor.authorAlkan M.Z.
dc.contributor.authorÜner A.
dc.contributor.authorGürüz Y.
dc.date.accessioned2019-10-26T21:49:27Z
dc.date.available2019-10-26T21:49:27Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractMalaria was expected to be a major problem during blood donation in Turkey due to existence of malaria cases in southeastern region of Turkey. The present study aimed for the first time, to investigate malaria in "donors deferred for malaria risk" and to determine the regional rates of malaria deferral in Turkey. Blood samples were collected from several Blood Banks of southeastern provinces where local malaria cases still exist and from Blood Bank of Ege University Medical School (EUMS) located in western Turkey where malaria is eradicated decades ago. Plasmodium spp. and specific antibodies were investigated by stained smears, antigen detection, PCR and ELISA. Among the donors deferred for malaria risk, Plasmodium spp. were not detected by microscopy, PCR or antigen detection. Seroprevalances were 2% and 3.92% in western and southeastern regions, respectively. Rate of donor deferral for malaria risk was 0.9% in EUMS and deferrals were exclusively because of travel to southeastern Turkey. In southeastern provinces, deferrals were mainly due to malaria like fever history. The present study first time assessed regional rates of donor deferral due to malaria risk in Turkey. Previously, malaria was expected to be a major problem during blood donation in Turkey due to existence of malaria cases in southeastern region of Turkey. The results of the study showed that 97% of the deferrals were unnecessary. In conclusion, to reduce unnecessary donor deferrals in Turkey, in addition to comprehensive questioning for malaria history, the usage of a malaria antibody screening method should be initiated prior to deferral decision. © 2012 Elsevier Ltd.en_US
dc.description.sponsorshipEge Üniversitesi: 2008TIP024en_US
dc.description.sponsorshipThe study was supported by the grant given by Ege University, Turkey (Grant number: 2008TIP024 ) to Y.G. The authors thank MR4 for providing with plasmids contributed by Peter A. Zimmerman. All authors read and approved the manuscript and declare that they have no competing interests. --en_US
dc.identifier.doi10.1016/j.transci.2012.03.008en_US
dc.identifier.endpage275en_US
dc.identifier.issn1473-0502
dc.identifier.issue3en_US
dc.identifier.pmid22464796en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage269en_US
dc.identifier.urihttps://doi.org/10.1016/j.transci.2012.03.008
dc.identifier.urihttps://hdl.handle.net/11454/18706
dc.identifier.volume46en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDeferralen_US
dc.subjectDonor questionnaireen_US
dc.subjectMalariaen_US
dc.subjectPlasmodiumen_US
dc.titleAction plan to regain unnecessary deferred blood donors due to malaria risk in Turkeyen_US
dc.typeArticleen_US

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