Is anti-Mullerian hormone an indicator of potential polycystic ovary syndrome in prepubertal girls with simple obesity?

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dc.contributor.authorKorkmaz, Özlem
dc.contributor.authorGökşen, Damla
dc.contributor.authorÖzen, Samim
dc.contributor.authorDarcan, Şükran
dc.date.accessioned2020-12-01T12:26:42Z
dc.date.available2020-12-01T12:26:42Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractKorkmaz ö, Gökşen D, özen S, Darcan Ş. Is anti-Mullerian hormone an indicator of potential polycystic ovary syndrome in prepubertal girls with simple obesity? Turk J Pediatr 2016; 58: 406-412.The aim of this anti-Mullerian hormone (AMH) levels in prepubertal obese girls are a predictive marker for polycystic ovary syndrome (PCOS) and to investigate the relationship between insulin resistance and AMH. Sixty girls with premature pubarche or obesity and 20 healthy controls between the ages of 6-9 were enrolled. of the patients, 22 (36.7%) were in the obese group (Group 1), 28 (46.7%) in the early pubarche group (Group 2) and 10 (16.6%) in the early pubarche + obese group (Group 3). Comparison of the subjects' fasting insulin and homeostatic model assessment insulin resistance (HOMA-IR) demonstrated significantly higher values for group 1 compared to group 2 (p=0.001 and 0.001) and, likewise, significantly higher values for group 3 compared to group 2. There was no significant differences between all groups for AMH levels.AMH levels were not significantly different in the obese girls compared to the other groups. There was also no relationship between AMH and insulin resistance in any of the groups. Further studies, however, are needed due the limited number of subjects in this study and in the absence of adequate relevant data.en_US
dc.identifier.endpage412en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.startpage406en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TWpRek1URTBOQT09
dc.identifier.urihttps://hdl.handle.net/11454/65661
dc.identifier.volume58en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPediatrien_US
dc.titleIs anti-Mullerian hormone an indicator of potential polycystic ovary syndrome in prepubertal girls with simple obesity?en_US
dc.typeArticleen_US

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